IgG4抗原
其它名稱:免疫球蛋白IgG4蛋白,IgG4 protein,IgG4蛋白
貨號(hào):G7043
應(yīng)用:Standard
特異性:Human IgG4
來(lái)源:重組蛋白
存貯:-20℃
免疫球蛋白IgG,由B淋巴細(xì)胞激活的漿細(xì)胞分泌產(chǎn)生。是人血清中最豐富的蛋白質(zhì)之一。IgG又分為四種亞型(IgG1,IgG2,IgG3,IgG4),最主要的是IgG1,而IgG4占總IgG的5%左右。
產(chǎn)品說(shuō)明
IgG1 immunoglobulin is most prevalent (>50%) and the IgG4 variety constitutes less than 5%. IgG4 has disulfide bonds linking the heavy chains unsteadily, allowing their separation and forming 2 antigen-binding sites, so that the bispecific antibody is asymmetric with an unclear in vivo role. IgG4 interacts with the Fc portion of IgG1–3 and not through the Fab-Fc, as occurs with other immunoglobulins, and has rheumatoid factor activity. Therefore, IgG4 has little or no cross-reactivity between antigens and rarely forms immune complexes having no complement activation capacity
This product is for research use only. It is not intended for diagnostic or therapeutic use.
注意事項(xiàng):
1.本品為蛋白質(zhì)制劑,未添加任何防腐劑和保護(hù)劑,在2-8℃可短期保存
2.本品作為診斷試劑原輔材料,不得直接用于診斷或治療。
關(guān)鍵字: IgG4蛋白;IgG4抗原;IgG4 protein;免疫球蛋白IgG4蛋白; 免疫球蛋白IgG;
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