中文名稱:NASP抗體 | 英文名稱:Rabbit Polyclonal NASP Antibody |
品牌: 艾普蒂 | 產(chǎn)地: 武漢 |
保存條件: Stored at -20°C for 5330 year. Avoid repeated freeze / thaw cycles. | 產(chǎn)品類別: 抗體 |
重組: 否 | 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA |
種屬反應性: Human,Mouse,Rat | 宿主: Rabbit |
偶聯(lián)物: 無 | 靶點: NASP |
WB | 咨詢技術 | Human,Mouse,Rat |
IF | 咨詢技術 | Human,Mouse,Rat |
IHC | 1/50-1/300 | Human,Mouse,Rat |
ICC | 技術咨詢 | Human,Mouse,Rat |
FCM | 咨詢技術 | Human,Mouse,Rat |
Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
Aliases | HMDRA1; FLB7527; PRO1999 |
WB Predicted band size | 85 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human NASP |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
+ +
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cell lysate, Primary antibody: P10169(NASP Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 minutes
The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P10169(NASP Antibody) at dilution 1/55. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P10169(NASP Antibody) at dilution 1/55. (Original magnification: ×200)
以下是關于NASP抗體的3篇代表性文獻摘要(文獻名稱及內(nèi)容為模擬示例):
---
1. **文獻名稱**: *NASP Antibodies as Biomarkers in Ovarian Cancer*
**作者**: Smith J, et al.
**摘要**: 研究探討了抗NASP抗體在卵巢癌患者血清中的表達水平及其臨床意義,發(fā)現(xiàn)高滴度抗體與晚期腫瘤分期和不良預后相關,提示其可作為潛在的非侵入性診斷標志物。
---
2. **文獻名稱**: *Autoimmune Response to NASP in Systemic Lupus Erythematosus*
**作者**: Chen L, et al.
**摘要**: 通過ELISA檢測系統(tǒng)性紅斑狼瘡(SLE)患者血清中的抗NASP自身抗體,發(fā)現(xiàn)其陽性率顯著高于健康對照組,提示NASP可能是SLE中新的自身抗原靶點,可能與疾病活動性相關。
---
3. **文獻名稱**: *Development of a Monoclonal Antibody Against Human tNASP for Chromatin Studies*
**作者**: Rodriguez M, et al.
**摘要**: 報道了一種特異性識別睪丸型NASP(tNASP)的單克隆抗體的開發(fā),驗證其在免疫組化和Western blot中的應用,并用于研究tNASP在精子發(fā)生過程中調(diào)控組蛋白H3轉(zhuǎn)運的機制。
---
注:以上內(nèi)容為模擬文獻,實際研究中請通過PubMed或Google Scholar檢索真實文獻(關鍵詞:NASP antibody, cancer, autoimmunity)。
**Background of NASP Antibody**
NASP (Nuclear Autoantigenic Sperm Protein) is a histone-binding chaperone critical for chromatin assembly, DNA replication, and repair. It exists in two isoforms: somatic (sNASP) and testicular (tNASP), with sNASP expressed in proliferating cells and tNASP specific to germ cells. NASP facilitates the transport and stability of histones H1 and H3. ensuring their availability during chromatin remodeling. Dysregulation of NASP is linked to cancer progression due to its role in promoting cell proliferation and genomic instability.
NASP antibodies are essential tools for studying its expression, localization, and function in cellular processes. They are widely used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to detect NASP levels in various tissues, particularly in cancer research where its overexpression correlates with tumor aggressiveness and poor prognosis. These antibodies also help investigate interactions between NASP and other chromatin-associated proteins, shedding light on mechanisms underlying epigenetic regulation and oncogenesis. Additionally, NASP antibodies aid in exploring its potential as a therapeutic target or biomarker in diseases characterized by abnormal cell proliferation, such as cancers or autoimmune disorders.
成立日期 | 2024-07-02 (2年) | 注冊資本 | 20萬人民幣 |
員工人數(shù) | 1-10人 | 年營業(yè)額 | ¥ 100萬以內(nèi) |
主營行業(yè) | 抗體,植物生物技術,細胞培養(yǎng),蛋白組學 | 經(jīng)營模式 | 貿(mào)易,工廠,試劑,定制,服務 |
產(chǎn)品名稱 | 價格 | 公司名稱 | 報價日期 | |
---|---|---|---|---|
¥1600.00 |
VIP10年
|
北京索萊寶科技有限公司
|
2025-08-11 | |
¥2580 |
VIP6年
|
上海澤葉生物科技有限公司
|
2025-08-11 | |
詢價 |
VIP3年
|
維百奧(北京)生物科技有限公司
|
2025-08-01 | |
¥1280 |
湖北艾普蒂生物工程有限公司
|
2025-06-04 |