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RAB41抗體,Rabbit Polyclonal RAB41 Antibody
  • RAB41抗體,Rabbit Polyclonal RAB41 Antibody
  • RAB41抗體,Rabbit Polyclonal RAB41 Antibody
  • RAB41抗體,Rabbit Polyclonal RAB41 Antibody

RAB41抗體—艾普蒂

價(jià)格 詢(xún)價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-19
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產(chǎn)品詳情

中文名稱(chēng):RAB41抗體英文名稱(chēng):Rabbit Polyclonal RAB41 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4587 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類(lèi)別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): RAB41
2025-05-19 RAB41抗體 Rabbit Polyclonal RAB41 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4587 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢(xún)技術(shù) Human,Mouse,Rat
IF咨詢(xún)技術(shù) Human,Mouse,Rat
IHC1/100-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢(xún) Human,Mouse,Rat
FCM咨詢(xún)技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

WB Predicted band size25 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human RAB41
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Mouse brain tissue lysate, Primary antibody: P09102(RAB41 Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09102(RAB41 Antibody) at dilution 1/110. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09102(RAB41 Antibody) at dilution 1/110. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于RAB41抗體的3篇參考文獻(xiàn)及其摘要概括(文獻(xiàn)標(biāo)題為虛構(gòu)示例,僅用于演示格式):

1. **標(biāo)題**:*Rab41 regulates Golgi apparatus integrity through interaction with Syntaxin 5*

**作者**:Yamamoto A, et al.

**摘要**:研究利用特異性RAB41抗體,發(fā)現(xiàn)RAB41通過(guò)與Syntaxin 5的相互作用維持高爾基體結(jié)構(gòu),并參與內(nèi)質(zhì)網(wǎng)到高爾基體的囊泡運(yùn)輸調(diào)控。

2. **標(biāo)題**:*RAB41 modulates autophagosome-lysosome fusion via GTPase activity*

**作者**:Chen L, et al.

**摘要**:通過(guò)抗RAB41抗體敲低實(shí)驗(yàn),證實(shí)RAB41的GTP酶活性影響自噬體與溶酶體融合,提示其在細(xì)胞自噬中的關(guān)鍵作用。

3. **標(biāo)題**:*Development and validation of a novel RAB41 monoclonal antibody for cancer biomarker studies*

**作者**:Smith J, et al.

**摘要**:報(bào)道了一種高特異性RAB41單克隆抗體的開(kāi)發(fā),并驗(yàn)證其在多種癌癥組織中檢測(cè)RAB41蛋白表達(dá)的可靠性,為腫瘤診斷提供潛在工具。

*注:以上文獻(xiàn)為示例,實(shí)際研究中RAB41相關(guān)抗體文獻(xiàn)較少,建議通過(guò)PubMed或Google Scholar以“RAB41 antibody”為關(guān)鍵詞檢索最新論文。*

       

背景信息

The RAB41 antibody is a tool used to study the RAB41 protein, a member of the RAB GTPase family, which regulates intracellular vesicle trafficking and membrane dynamics. RAB proteins are small GTPases that cycle between active (GTP-bound) and inactive (GDP-bound) states, acting as molecular switches to control cargo transport, organelle biogenesis, and membrane fusion. RAB41. though less characterized compared to other RABs (e.g., RAB5. RAB7), is implicated in Golgi-to-endosome trafficking and secretory pathways. It may play roles in maintaining Golgi structure, lysosomal function, or autophagy. Antibodies against RAB41 enable researchers to detect its expression, localization, and interactions via techniques like Western blotting, immunofluorescence, or immunoprecipitation. These tools help elucidate its physiological functions and potential involvement in diseases, such as cancer or neurodegenerative disorders, where vesicle trafficking dysregulation is common. However, RAB41's precise mechanisms remain unclear, partly due to limited studies and antibody specificity challenges. Commercial RAB41 antibodies are typically polyclonal or monoclonal, raised against peptide epitopes, and require validation using knockout controls to confirm target specificity. Ongoing research aims to clarify RAB41's role in cellular pathways and its relevance to human health.
       
關(guān)鍵字: RAB41抗體;RAB41;RAB41 Antibody;

公司簡(jiǎn)介

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主營(yíng)行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類(lèi)型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
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