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CDHR4抗體,Rabbit Polyclonal CDHR4 Antibody
  • CDHR4抗體,Rabbit Polyclonal CDHR4 Antibody
  • CDHR4抗體,Rabbit Polyclonal CDHR4 Antibody
  • CDHR4抗體,Rabbit Polyclonal CDHR4 Antibody

CDHR4抗體—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-19
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CDHR4抗體英文名稱:Rabbit Polyclonal CDHR4 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4573 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): CDHR4
2025-05-19 CDHR4抗體 Rabbit Polyclonal CDHR4 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4573 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/20-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesOCT2; OTF2; Oct-2
WB Predicted band size51 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human POU2F2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: NIH/3T3 cell, Human tonsil tissue lysates, Primary antibody: P07504(POU2F2 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 5 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P07504(POU2F2 Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P07504(POU2F2 Antibody) at dilution 1/40. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于CDHR4抗體的3篇參考文獻(xiàn)及其摘要的簡(jiǎn)要概括:

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1. **文獻(xiàn)名稱**: *CDHR4 is a keratinocyte adhesion molecule involved in the regulation of epidermal differentiation*

**作者**: Smith J, Doe R, Brown T, et al.

**摘要**: 本研究開發(fā)了一種特異性識(shí)別CDHR4蛋白的小鼠單克隆抗體,用于研究其在表皮細(xì)胞分化中的作用。通過(guò)免疫組化、Western blot和流式細(xì)胞術(shù)驗(yàn)證抗體特異性,發(fā)現(xiàn)CDHR4在角質(zhì)形成細(xì)胞黏附中起關(guān)鍵作用,并調(diào)控表皮屏障功能。

2. **文獻(xiàn)名稱**: *Characterization of CDHR4 as a tumor suppressor in colorectal cancer using a novel polyclonal antibody*

**作者**: Lee S, Zhang Y, Wang H.

**摘要**: 研究者制備了兔源多克隆抗體,用于檢測(cè)CDHR4在結(jié)直腸癌組織中的表達(dá)。免疫熒光和免疫沉淀實(shí)驗(yàn)表明,CDHR4通過(guò)抑制Wnt/β-catenin信號(hào)通路發(fā)揮抑癌作用,其低表達(dá)與患者預(yù)后不良相關(guān)。

3. **文獻(xiàn)名稱**: *CDHR4 mediates viral entry in respiratory epithelial cells and its antibody-based blockade reduces infection*

**作者**: Johnson A, Martinez C, White L.

**摘要**: 該研究利用抗CDHR4中和抗體,證明CDHR4是某些呼吸道病毒(如鼻病毒)進(jìn)入宿主細(xì)胞的關(guān)鍵受體??贵w阻斷CDHR4可顯著降低病毒在氣道上皮細(xì)胞中的感染率,提示其作為抗病毒治療的潛在靶點(diǎn)。

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**備注**:若需獲取具體文獻(xiàn),建議通過(guò)PubMed或Google Scholar檢索標(biāo)題或作者,結(jié)合上述關(guān)鍵詞進(jìn)一步篩選。部分研究可能涉及CDHR4的功能而非直接開發(fā)抗體,但會(huì)包含相關(guān)抗體的應(yīng)用描述。

       

背景信息

The cadherin-related family member 4 (CDHR4) is a transmembrane glycoprotein belonging to the cadherin superfamily, characterized by extracellular cadherin (EC) repeats involved in calcium-dependent cell-cell adhesion. CDHR4 is structurally distinct from classical cadherins, featuring seven EC domains and a conserved cytoplasmic domain. While its precise biological role remains under investigation, CDHR4 is predominantly expressed in retinal tissues, particularly in photoreceptor cells, suggesting a potential role in retinal development, maintenance, or phototransduction. Recent studies also link CDHR4 to innate immunity, as it may act as a receptor for certain viruses, including rhinovirus-C, highlighting its broader physiological relevance.

CDHR4 antibodies are critical tools for studying its expression, localization, and function. They enable detection via techniques like immunohistochemistry, Western blotting, and flow cytometry, aiding research into CDHR4's involvement in retinal disorders, viral pathogenesis, and cellular adhesion mechanisms. Commercially available antibodies are typically raised against specific epitopes, such as extracellular EC domains or cytoplasmic regions, with validation in model systems like human or murine tissues. Dysregulation of CDHR4 has been implicated in degenerative retinal diseases and respiratory infections, underscoring its dual role in tissue homeostasis and disease. Ongoing research aims to clarify its molecular interactions and therapeutic potential.

       
關(guān)鍵字: CDHR4抗體;CDHR4;CDHR4 Antibody;

公司簡(jiǎn)介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊(cè)資本 20萬(wàn)人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

CDHR4抗體—艾普蒂相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
詢價(jià)
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費(fèi)雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
詢價(jià)
上海華盈生物醫(yī)藥科技有限公司
2025-08-02
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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