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LEFTY2抗體,Rabbit Polyclonal LEFTY2 Antibody
  • LEFTY2抗體,Rabbit Polyclonal LEFTY2 Antibody
  • LEFTY2抗體,Rabbit Polyclonal LEFTY2 Antibody
  • LEFTY2抗體,Rabbit Polyclonal LEFTY2 Antibody

LEFTY2抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-19
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:LEFTY2抗體英文名稱:Rabbit Polyclonal LEFTY2 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4402 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: LEFTY2
2025-05-19 LEFTY2抗體 Rabbit Polyclonal LEFTY2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4402 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB1/500-1/2000 Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/10-1/50 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesEBAF; LEFTA; TGFB4; LEFTYA
WB Predicted band size41 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal muscle tissue, Primary antibody: P08851(LEFTY2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08851(LEFTY2 Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P08851(LEFTY2 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于LEFTY2抗體的3篇參考文獻(xiàn)的示例(注:文獻(xiàn)信息為示例,實際引用請核實原文):

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1. **文獻(xiàn)名稱**: "Left-right asymmetry in embryonic development: role of Lefty2 in the mouse"

**作者**: Meno, C. et al.

**摘要**: 該研究利用LEFTY2抗體在小鼠胚胎中檢測蛋白表達(dá),發(fā)現(xiàn)LEFTY2通過拮抗Nodal信號通路調(diào)控胚胎左右軸形成,揭示了其在早期發(fā)育中的關(guān)鍵作用。

---

2. **文獻(xiàn)名稱**: "Lefty2 as a biomarker in ovarian cancer progression"

**作者**: Tanaka, M. et al.

**摘要**: 通過免疫組化(使用LEFTY2抗體)分析卵巢癌組織,發(fā)現(xiàn)LEFTY2高表達(dá)與腫瘤轉(zhuǎn)移和不良預(yù)后相關(guān),提示其可作為潛在治療靶點。

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3. **文獻(xiàn)名稱**: "Regulation of TGF-β signaling by Lefty2 in human embryonic stem cells"

**作者**: Saijoh, Y. et al.

**摘要**: 研究使用LEFTY2抗體進(jìn)行蛋白質(zhì)印跡和免疫熒光實驗,證實LEFTY2通過抑制Smad2/3磷酸化調(diào)控TGF-β通路,影響人胚胎干細(xì)胞的自我更新與分化。

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4. **文獻(xiàn)名稱**: "Lefty2 antibody-based detection in breast cancer metastasis"

**作者**: Chung, J. et al.

**摘要**: 利用LEFTY2抗體的ELISA和免疫組化方法,發(fā)現(xiàn)LEFTY2在乳腺癌轉(zhuǎn)移患者的血清中顯著升高,提示其作為液體活檢標(biāo)志物的潛力。

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(注:以上文獻(xiàn)為示例,實際研究請參考PubMed或SciFinder等數(shù)據(jù)庫的權(quán)威文獻(xiàn)。)

       

背景信息

The LEFTY2 antibody is a crucial tool in studying the role of LEFTY2 (Left-Right Determination Factor 2), a secreted protein belonging to the TGF-β (transforming growth factor-beta) superfamily. LEFTY2. also known as endometrial bleeding-associated factor (Ebaf), is primarily involved in embryonic development, particularly in establishing left-right asymmetry during organogenesis. It acts as an antagonist of Nodal and BMP (bone morphogenetic protein) signaling pathways, regulating cell differentiation, tissue patterning, and stem cell maintenance. Dysregulation of LEFTY2 has been linked to developmental disorders, cancer progression, and reproductive health issues, including endometrial remodeling and recurrent pregnancy loss.

LEFTY2 antibodies are widely used in research to detect and quantify LEFTY2 protein expression in various biological samples through techniques like Western blotting, immunohistochemistry, and immunofluorescence. These antibodies help elucidate LEFTY2's spatial-temporal expression patterns, its interactions with signaling molecules, and its role in pathological conditions. For instance, studies using LEFTY2 antibodies have revealed its tumor-suppressive effects in certain cancers by inhibiting epithelial-mesenchymal transition (EMT), while other research highlights its involvement in immune modulation and tissue fibrosis. The development of specific, high-affinity LEFTY2 antibodies continues to advance our understanding of developmental biology, oncology, and regenerative medicine.

       
關(guān)鍵字: LEFTY2抗體;LEFTY2;LEFTY2 Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

LEFTY2抗體—艾普蒂相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
詢價
VIP1年
上海切爾齊生物科技有限公司
2025-05-30
¥2900
VIP4年
上海博爾森生物科技有限公司
2025-08-01
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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