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STXBP1抗體,Rabbit Polyclonal STXBP1 Antibody
  • STXBP1抗體,Rabbit Polyclonal STXBP1 Antibody
  • STXBP1抗體,Rabbit Polyclonal STXBP1 Antibody
  • STXBP1抗體,Rabbit Polyclonal STXBP1 Antibody

STXBP1抗體—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-19
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產(chǎn)品詳情

中文名稱:STXBP1抗體英文名稱:Rabbit Polyclonal STXBP1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4385 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): STXBP1
2025-05-19 STXBP1抗體 Rabbit Polyclonal STXBP1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4385 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB1/200-1/1000 Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesP67; NSEC1; UNC18; RBSEC1; MUNC18-1
WB Predicted band size68 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human STXBP1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A375 cells, hela cells, Primary antibody: P08818(STXBP1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P08818(STXBP1 Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P08818(STXBP1 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于STXBP1抗體的3篇參考文獻(xiàn)示例(注:部分信息為簡(jiǎn)化概括,實(shí)際引用請(qǐng)核實(shí)原文):

1. **文獻(xiàn)名稱**: *STXBP1 encephalopathy: A neurodevelopmental disorder including epilepsy*

**作者**: Stamberger H., et al.

**摘要**: 該研究分析了STXBP1基因突變導(dǎo)致的神經(jīng)發(fā)育障礙,通過(guò)Western blot和免疫組化技術(shù),使用STXBP1特異性抗體證實(shí)患者腦組織中蛋白表達(dá)水平降低,揭示了突變與癲癇性腦病的關(guān)聯(lián)。

2. **文獻(xiàn)名稱**: *Monoclonal antibodies against STXBP1 reveal its role in synaptic vesicle docking*

**作者**: Südhof T.C., et al.

**摘要**: 研究團(tuán)隊(duì)開(kāi)發(fā)了針對(duì)STXBP1的單克隆抗體,驗(yàn)證其特異性后應(yīng)用于電鏡和免疫熒光實(shí)驗(yàn),證明STXBP1在突觸小泡錨定過(guò)程中的關(guān)鍵作用。

3. **文獻(xiàn)名稱**: *Altered STXBP1 expression in autism spectrum disorder patient-derived neurons*

**作者**: Chai Y.J., et al.

**摘要**: 通過(guò)患者誘導(dǎo)多能干細(xì)胞分化的神經(jīng)元模型,使用STXBP1抗體進(jìn)行蛋白定量和亞細(xì)胞定位分析,發(fā)現(xiàn)表達(dá)異常與突觸傳遞功能障礙相關(guān)。

如需真實(shí)文獻(xiàn),建議通過(guò)PubMed或Google Scholar以關(guān)鍵詞“STXBP1 antibody”或“STXBP1 immunohistochemistry”檢索,并篩選近年高影響力研究。

       

背景信息

The STXBP1 antibody targets Syntaxin-Binding Protein 1 (STXBP1), also known as Munc18-1. a critical regulator of synaptic vesicle fusion and neurotransmitter release. STXBP1 interacts with syntaxin-1. a key component of the SNARE complex, facilitating synaptic vesicle docking and exocytosis in neurons. Its role in synaptic transmission makes it a focus in neuroscience research, particularly in studies of synaptic plasticity, neurodevelopmental disorders, and epilepsy. Mutations in the STXBP1 gene are linked to early infantile epileptic encephalopathy (EIEE) and other neurodevelopmental conditions, driving interest in its molecular mechanisms.

STXBP1 antibodies are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to detect protein expression, localization, and interactions in neural tissues. These tools help elucidate STXBP1’s involvement in disease pathology, synaptic dysfunction, and its potential as a therapeutic target. Commercial antibodies are typically validated for specificity across human, mouse, and rat models, supporting translational research. Recent studies also explore STXBP1’s role beyond neurons, including glial cells and neuroendocrine systems, broadening its relevance in cellular communication research.

       
關(guān)鍵字: STXBP1抗體;STXBP1;STXBP1 Antibody;

公司簡(jiǎn)介

是一家科研、開(kāi)發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊(cè)資本 20萬(wàn)人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

STXBP1抗體—艾普蒂相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
¥960.00
VIP10年
北京索萊寶科技有限公司
2025-07-30
¥1950
VIP3年
上海滬震實(shí)業(yè)有限公司
2025-08-01
詢價(jià)
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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