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SSX1抗體,Rabbit Polyclonal SSX1 Antibody
  • SSX1抗體,Rabbit Polyclonal SSX1 Antibody
  • SSX1抗體,Rabbit Polyclonal SSX1 Antibody
  • SSX1抗體,Rabbit Polyclonal SSX1 Antibody

SSX1抗體—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-19
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:SSX1抗體英文名稱:Rabbit Polyclonal SSX1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4379 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): SSX1
2025-05-19 SSX1抗體 Rabbit Polyclonal SSX1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4379 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB1/200-1/1000 Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC咨詢技術(shù) Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesSSRC; CT5.1
WB Predicted band size22 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human SSX1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: K562 cells, Primary antibody: P08810(SSX1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


           

參考文獻(xiàn)

以下是關(guān)于SSX1抗體的示例參考文獻(xiàn)(注:部分信息為示例性質(zhì),實(shí)際文獻(xiàn)需通過學(xué)術(shù)數(shù)據(jù)庫(kù)驗(yàn)證):

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1. **標(biāo)題**: *"SSX1 as a diagnostic marker for synovial sarcoma: Development of a novel monoclonal antibody"*

**作者**: Smith A, et al.

**摘要**: 研究團(tuán)隊(duì)開發(fā)了一種針對(duì)SSX1蛋白的單克隆抗體,通過免疫組化驗(yàn)證其在滑膜肉瘤診斷中的特異性。該抗體能有效區(qū)分SSX1與其他SSX家族蛋白,并在臨床樣本中檢測(cè)到滑膜肉瘤特異性融合蛋白的表達(dá)。

2. **標(biāo)題**: *"Immunodetection of cancer-testis antigen SSX1 in epithelial malignancies"*

**作者**: Lee B, et al.

**摘要**: 本研究利用SSX1抗體探究其在多種上皮源性腫瘤(如肺癌、乳腺癌)中的表達(dá)。結(jié)果顯示,SSX1在部分癌癥中異常激活,提示其可能作為免疫治療靶點(diǎn)或預(yù)后標(biāo)志物。

3. **標(biāo)題**: *"SSX1 antibody-based detection of minimal residual disease in synovial sarcoma"*

**作者**: Tanaka K, et al.

**摘要**: 通過高靈敏度的SSX1抗體建立了一種檢測(cè)滑膜肉瘤術(shù)后微小殘留病灶的方法,證實(shí)其在血液和骨髓樣本中的診斷潛力,為臨床監(jiān)測(cè)復(fù)發(fā)提供新工具。

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**建議**:如需具體文獻(xiàn),可通過PubMed或Google Scholar搜索關(guān)鍵詞“SSX1 antibody”、“SSX1 immunohistochemistry”或“SSX1 cancer”,并篩選近10年研究以獲取最新進(jìn)展。

       

背景信息

The SSX1 antibody is a valuable tool in cancer research, particularly in studying malignancies associated with the SSX gene family. SSX1. a member of the SSX (synovial sarcoma X breakpoint) gene family, encodes a cancer-testis antigen (CTA) normally expressed in germ cells but aberrantly reactivated in various cancers. SSX proteins are implicated in transcriptional regulation and chromatin remodeling. SSX1 gained prominence due to its role in synovial sarcoma, where chromosomal translocation t(X;18) fuses SSX1 (or SSX2/SSX4) with the SS18 gene, producing an oncogenic SS18-SSX fusion protein that drives tumorigenesis by disrupting epigenetic regulators.

SSX1 antibodies are primarily used to detect SSX1 protein expression in research and diagnostic settings. They help identify SSX1-positive tumors, characterize subcellular localization (nuclear/cytoplasmic), and study its interaction with proteins like Polycomb repressive complexes. Commercially available SSX1 antibodies include monoclonal and polyclonal variants validated for techniques like immunohistochemistry, Western blotting, and immunofluorescence. Challenges include cross-reactivity with other SSX family members (SSX2-SSX9) due to high sequence homology, necessitating careful validation. Clinically, SSX1 is explored as a biomarker and immunotherapy target, with efforts to develop SSX1-directed CAR-T cells or vaccines. However, its restricted normal tissue expression and tumor-specific reactivation make it a promising but still emerging target in precision oncology.

       
關(guān)鍵字: SSX1抗體;SSX1;SSX1 Antibody;

公司簡(jiǎn)介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊(cè)資本 20萬人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營(yíng)行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

SSX1抗體—艾普蒂相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
¥1950
VIP3年
上海滬震實(shí)業(yè)有限公司
2025-08-08
¥1600.00
VIP10年
北京索萊寶科技有限公司
2025-08-07
詢價(jià)
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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