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PYGL抗體,Rabbit Polyclonal PYGL Antibody
  • PYGL抗體,Rabbit Polyclonal PYGL Antibody
  • PYGL抗體,Rabbit Polyclonal PYGL Antibody
  • PYGL抗體,Rabbit Polyclonal PYGL Antibody

PYGL抗體—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-19
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:PYGL抗體英文名稱:Rabbit Polyclonal PYGL Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4285 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): PYGL
2025-05-19 PYGL抗體 Rabbit Polyclonal PYGL Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4285 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB1/200-1/1000 Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesGSD6
WB Predicted band size97 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human PYGL
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: PC3 cells, human fetal liver tissue, Primary antibody: P08657(PYGL Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08657(PYGL Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human brain  tissue using P08657(PYGL Antibody) at dilution 1/20. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是模擬生成的3篇關(guān)于PYGL抗體的文獻(xiàn)示例(僅供參考,實(shí)際文獻(xiàn)請(qǐng)通過(guò)學(xué)術(shù)數(shù)據(jù)庫(kù)查詢):

1. **文獻(xiàn)名稱**:*"Phosphorylase L (PYGL) antibody as a diagnostic marker for hepatocellular carcinoma: Immunohistochemical analysis"*

**作者**:Zhang Y, et al.

**摘要**:研究通過(guò)免疫組化驗(yàn)證PYGL抗體在肝細(xì)胞癌組織中的高特異性表達(dá),提示PYGL可能作為肝癌的潛在診斷標(biāo)志物,并與患者預(yù)后相關(guān)。

2. **文獻(xiàn)名稱**:*"Role of PYGL in glycogen metabolism: Insights from antibody-based knockdown studies"*

**作者**:Smith JL, et al.

**摘要**:利用PYGL抗體進(jìn)行蛋白質(zhì)印跡及功能研究,發(fā)現(xiàn)PYGL缺失導(dǎo)致肝細(xì)胞糖原分解受阻,揭示了其在能量代謝中的關(guān)鍵作用。

3. **文獻(xiàn)名稱**:*"Development of a novel monoclonal PYGL antibody for detecting glycogen storage disease type VI"*

**作者**:Kumar R, et al.

**摘要**:報(bào)道一種高靈敏度的PYGL單克隆抗體的開(kāi)發(fā),用于糖原貯積癥VI型的分子診斷,并通過(guò)ELISA和免疫熒光驗(yàn)證其臨床應(yīng)用潛力。

4. **文獻(xiàn)名稱**:*"PYGL phosphorylation dynamics revealed by phospho-specific antibodies in metabolic stress"*

**作者**:Chen H, et al.

**摘要**:通過(guò)磷酸化特異性PYGL抗體研究其在缺氧和能量應(yīng)激下的修飾變化,闡明了PYGL活性調(diào)控的分子機(jī)制。

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建議通過(guò) **PubMed** 或 **Google Scholar** 搜索關(guān)鍵詞“PYGL antibody”、“glycogen phosphorylase L” + “diagnostic/therapeutic”獲取真實(shí)文獻(xiàn)。

       

背景信息

PYGL antibody targets the PYGL gene-encoded protein, glycogen phosphorylase liver-type, a key enzyme in glycogenolysis. PYGL catalyzes the cleavage of glycogen into glucose-1-phosphate, a critical step in maintaining blood glucose levels during fasting. Primarily expressed in the liver, PYGL activity is tightly regulated by allosteric effectors and phosphorylation, with hormonal signals (e.g., glucagon) activating it via cAMP-dependent pathways. Dysregulation of PYGL is linked to metabolic disorders, including glycogen storage disease type VI (Hers disease), characterized by hepatomegaly and hypoglycemia.

PYGL antibodies are essential tools in research, enabling the detection and quantification of PYGL protein in tissues or cell lysates using techniques like Western blotting, immunohistochemistry, and immunofluorescence. These antibodies aid in studying hepatic glucose metabolism, pathological mechanisms of glycogen-related diseases, and potential therapeutic targets. Additionally, they help investigate PYGL's role in hepatocellular carcinoma, where altered glycogen metabolism is observed. Commercial PYGL antibodies are typically raised in rabbits or mice, validated for specificity to avoid cross-reactivity with muscle (PYGM) or brain (PYGB) isoforms. Their application extends to preclinical models, enhancing understanding of metabolic adaptation and liver function.

       
關(guān)鍵字: PYGL抗體;PYGL;PYGL Antibody;

公司簡(jiǎn)介

是一家科研、開(kāi)發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊(cè)資本 20萬(wàn)人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤(pán)

PYGL抗體—艾普蒂相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
詢價(jià)
VIP5年
上海冠導(dǎo)生物工程有限公司
2025-08-03
¥1600.00
VIP10年
北京索萊寶科技有限公司
2025-07-30
¥1950
VIP3年
上海滬震實(shí)業(yè)有限公司
2025-08-01
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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