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NRIP1抗體,Rabbit Polyclonal NRIP1 Antibody
  • NRIP1抗體,Rabbit Polyclonal NRIP1 Antibody
  • NRIP1抗體,Rabbit Polyclonal NRIP1 Antibody
  • NRIP1抗體,Rabbit Polyclonal NRIP1 Antibody

NRIP1抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-19
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:NRIP1抗體英文名稱:Rabbit Polyclonal NRIP1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4226 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: NRIP1
2025-05-19 NRIP1抗體 Rabbit Polyclonal NRIP1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4226 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/100-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesCAKUT3; RIP140
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human NRIP1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P08574(NRIP1 Antibody) at dilution 1/100. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P08574(NRIP1 Antibody) at dilution 1/100. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于NRIP1抗體的模擬參考文獻(xiàn)示例(注:文獻(xiàn)為虛構(gòu)示例,僅供格式參考):

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1. **文獻(xiàn)名稱**:*NRIP1 Antibody-Based Detection of RIP140 in Estrogen Receptor-Positive Breast Cancer*

**作者**:Smith A, et al.

**摘要**:研究利用兔源多克隆NRIP1抗體,通過Western blot和免疫組化技術(shù),證實NRIP1在乳腺癌中與雌激素受體α(ERα)共定位,并增強(qiáng)腫瘤細(xì)胞對雌激素的敏感性,提示其作為治療靶點的潛力。

2. **文獻(xiàn)名稱**:*Development of a Monoclonal NRIP1 Antibody for Metabolic Tissue Analysis*

**作者**:Chen L, et al.

**摘要**:報道一種新型小鼠單克隆NRIP1抗體的開發(fā)與驗證,應(yīng)用于脂肪組織和肝臟樣本的免疫熒光染色,揭示NRIP1在調(diào)控脂質(zhì)代謝中的組織特異性表達(dá)模式。

3. **文獻(xiàn)名稱**:*NRIP1 Knockdown and Antibody Validation in Ovarian Cancer Models*

**作者**:Wang Y, et al.

**摘要**:通過siRNA沉默NRIP1基因,結(jié)合商業(yè)化NRIP1抗體進(jìn)行流式細(xì)胞術(shù)分析,證明NRIP1高表達(dá)與卵巢癌細(xì)胞化療耐藥性相關(guān),機(jī)制涉及NF-κB通路激活。

4. **文獻(xiàn)名稱**:*ChIP-Seq Analysis Using NRIP1 Antibody Reveals Genome-Wide Binding Sites*

**作者**:Kim T, et al.

**摘要**:采用ChIP-seq技術(shù)結(jié)合特異性NRIP1抗體,系統(tǒng)繪制NRIP1在人類基因組中的結(jié)合位點,發(fā)現(xiàn)其優(yōu)先結(jié)合代謝相關(guān)基因啟動子區(qū)域,調(diào)控糖酵解和氧化磷酸化過程。

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**建議**:如需真實文獻(xiàn),可通過PubMed或Google Scholar搜索關(guān)鍵詞“NRIP1 antibody”、“RIP140 antibody application”等,并篩選涉及實驗方法學(xué)(如Western blot、IHC)的研究。

       

背景信息

**Background of NRIP1 Antibody**

The Nuclear Receptor Interacting Protein 1 (NRIP1), also known as RIP140 (Receptor-Interacting Protein 140), is a transcriptional coregulator that modulates the activity of nuclear receptors and other transcription factors. It plays a critical role in diverse biological processes, including energy metabolism, reproduction, and circadian rhythm regulation. NRIP1 interacts with ligand-bound nuclear receptors (e.g., estrogen receptor, thyroid hormone receptor) to either enhance or repress their transcriptional activity, depending on cellular context. Dysregulation of NRIP1 has been implicated in metabolic disorders, cancer progression, and reproductive abnormalities.

Antibodies targeting NRIP1 are essential tools for studying its expression, localization, and molecular interactions. They are widely used in techniques such as Western blotting, immunoprecipitation, immunohistochemistry, and immunofluorescence to investigate NRIP1's role in cellular pathways and disease mechanisms. Commercial NRIP1 antibodies are typically raised against specific epitopes (e.g., human or mouse-derived peptide sequences) and validated for specificity and sensitivity across applications. Research utilizing these antibodies has advanced understanding of NRIP1's dual role as a coactivator or corepressor in hormone signaling and its potential as a therapeutic target in metabolic syndromes and hormone-dependent cancers. Quality validation, including knockout controls, is crucial to ensure antibody reliability in experimental settings.

       
關(guān)鍵字: NRIP1抗體;NRIP1;NRIP1 Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

NRIP1抗體—艾普蒂相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
詢價
上海華盈生物醫(yī)藥科技有限公司
2025-08-02
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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