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NDUFA5抗體,Rabbit Polyclonal NDUFA5 Antibody
  • NDUFA5抗體,Rabbit Polyclonal NDUFA5 Antibody
  • NDUFA5抗體,Rabbit Polyclonal NDUFA5 Antibody
  • NDUFA5抗體,Rabbit Polyclonal NDUFA5 Antibody

NDUFA5抗體—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-19
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產(chǎn)品詳情

中文名稱:NDUFA5抗體英文名稱:Rabbit Polyclonal NDUFA5 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4210 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): NDUFA5
2025-05-19 NDUFA5抗體 Rabbit Polyclonal NDUFA5 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4210 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesB13; NUFM; UQOR13; CI-13kB; CI-13KD-B
WB Predicted band size13 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human NDUFA5
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human bladder carcinoma tissue, Human fetal brain tissue, Primary antibody: P08548(NDUFA5 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P08548(NDUFA5 Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08548(NDUFA5 Antibody) at dilution 1/40. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于NDUFA5抗體的3篇示例參考文獻(xiàn)(注:以下為模擬內(nèi)容,實(shí)際文獻(xiàn)需通過學(xué)術(shù)數(shù)據(jù)庫檢索確認(rèn)):

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1. **文獻(xiàn)名稱**: "NDUFA5 expression is reduced in Parkinson's disease cybrid cell models"

**作者**: Smith J, et al.

**摘要**: 本研究利用NDUFA5抗體通過Western blot分析帕金森病細(xì)胞模型中線粒體復(fù)合體I亞基的表達(dá)水平,發(fā)現(xiàn)NDUFA5蛋白顯著下調(diào),提示其可能參與多巴胺能神經(jīng)元的線粒體功能障礙。

2. **文獻(xiàn)名稱**: "Antibody-based profiling of mitochondrial complex I subunits in colorectal cancer"

**作者**: Lee S, et al.

**摘要**: 通過免疫組織化學(xué)(IHC)和免疫印跡(WB)技術(shù),使用NDUFA5抗體檢測結(jié)直腸癌組織中線粒體復(fù)合體I的分布及表達(dá)量,發(fā)現(xiàn)NDUFA5的低表達(dá)與患者預(yù)后不良相關(guān)。

3. **文獻(xiàn)名稱**: "Characterization of a novel NDUFA5 knockout mouse using specific polyclonal antibodies"

**作者**: García-Ruiz C, et al.

**摘要**: 研究團(tuán)隊(duì)開發(fā)并驗(yàn)證了一種高特異性NDUFA5多克隆抗體,用于檢測基因敲除小鼠模型中NDUFA5蛋白的缺失,證實(shí)其在維持復(fù)合體I組裝中的關(guān)鍵作用。

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如需真實(shí)文獻(xiàn),建議在PubMed或Google Scholar中檢索關(guān)鍵詞“NDUFA5 antibody”、“NDUFA5 mitochondrial complex I”等,并篩選應(yīng)用該抗體的實(shí)驗(yàn)研究。

       

背景信息

The NDUFA5 antibody is a crucial tool for studying mitochondrial complex I (NADH:ubiquinone oxidoreductase), a key component of the electron transport chain. NDUFA5 (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5) is a nuclear-encoded subunit of complex I, which plays a vital role in ATP synthesis by facilitating electron transfer from NADH to ubiquinone. Dysregulation of NDUFA5 has been linked to mitochondrial disorders, neurodegenerative diseases (e.g., Parkinson’s and Alzheimer’s), and certain cancers.

NDUFA5 antibodies are widely used in research to detect protein expression levels via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). These antibodies help investigate mitochondrial dysfunction mechanisms, assess complex I assembly defects, and explore metabolic adaptations in diseases. Species specificity typically covers human, mouse, and rat samples, with common hosts including rabbit (polyclonal) and mouse (monoclonal).

Validation of NDUFA5 antibodies often involves knockout cell lines or tissue controls to confirm specificity. Recent studies also utilize these antibodies to probe NDUFA5’s role in oxidative stress responses and its potential as a biomarker for metabolic syndromes. Researchers must optimize experimental conditions, as mitochondrial protein extraction and antibody dilution ratios can significantly impact results.

       
關(guān)鍵字: NDUFA5抗體;NDUFA5;NDUFA5 Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

NDUFA5抗體—艾普蒂相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
¥960.00
VIP10年
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2025-07-30
¥1950
VIP3年
上海滬震實(shí)業(yè)有限公司
2025-08-01
詢價(jià)
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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