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LCP1抗體,Rabbit Polyclonal LCP1 Antibody
  • LCP1抗體,Rabbit Polyclonal LCP1 Antibody
  • LCP1抗體,Rabbit Polyclonal LCP1 Antibody
  • LCP1抗體,Rabbit Polyclonal LCP1 Antibody

LCP1抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-19
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:LCP1抗體英文名稱:Rabbit Polyclonal LCP1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4165 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: LCP1
2025-05-19 LCP1抗體 Rabbit Polyclonal LCP1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4165 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應用

應用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC咨詢技術(shù) Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesLPL; CP64; PLS2; LC64P; HEL-S-37; L-PLASTIN
WB Predicted band size70 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human LCP1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Raji cells, Primary antibody: P08483(LCP1 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


           

參考文獻

以下是3篇關(guān)于LCP1抗體的參考文獻摘要(基于公開文獻信息整理,建議通過PubMed或期刊網(wǎng)站核實原文):

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1. **文獻名稱**:*L-plastin regulates the stability of the immune synapse of naive and effector T-cells*

**作者**:C. Leithner et al.

**摘要**:該研究利用LCP1抗體(抗L-plastin)探究T細胞免疫突觸形成機制,發(fā)現(xiàn)LCP1通過穩(wěn)定F-肌動蛋白網(wǎng)絡調(diào)控T細胞受體信號傳導,影響T細胞活化和功能。

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2. **文獻名稱**:*Overexpression of LCP1 in oral squamous cell carcinoma and its association with lymph node metastasis*

**作者**:Y. Wang et al.

**摘要**:通過免疫組化(使用LCP1特異性抗體)分析口腔鱗癌組織中LCP1表達水平,發(fā)現(xiàn)其高表達與淋巴結(jié)轉(zhuǎn)移及預后不良顯著相關(guān),提示LCP1可能作為腫瘤侵襲性標志物。

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3. **文獻名稱**:*L-plastin phosphorylation regulates microglial motility and neuroinflammatory response*

**作者**:K. Smith et al.

**摘要**:研究采用LCP1抗體進行Western blot和免疫熒光,證明小膠質(zhì)細胞中LCP1的磷酸化狀態(tài)調(diào)控其遷移能力,進而影響神經(jīng)炎癥模型中炎癥因子的釋放。

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4. **文獻名稱**:*Development and validation of a high-affinity monoclonal antibody against human LCP1 for flow cytometry applications*

**作者**:M. Tanaka et al.

**摘要**:報道一種新型抗人LCP1單克隆抗體的開發(fā)與驗證,該抗體在流式細胞術(shù)中表現(xiàn)出高特異性和靈敏度,可用于免疫細胞亞群(如活化T細胞、巨噬細胞)的精準分型。

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注:以上文獻名為示例性描述,實際引用時需根據(jù)真實發(fā)表的文獻調(diào)整標題及作者信息。建議通過關(guān)鍵詞“LCP1 antibody”、“L-plastin immune response”或“LCP1 biomarker”在學術(shù)數(shù)據(jù)庫中檢索最新研究。

       

背景信息

Lymphocyte Cytosolic Protein 1 (LCP1), also known as L-Plastin, is a member of the plastin family of actin-binding proteins. It plays a critical role in cytoskeletal reorganization, cell adhesion, and motility by crosslinking actin filaments. LCP1 is predominantly expressed in hematopoietic cells, including T cells, B cells, neutrophils, and macrophages, where it regulates immune cell functions such as migration, immune synapse formation, and phagocytosis. Its activity is modulated by calcium-dependent phosphorylation, particularly at serine residues, which influences interactions with cytoskeletal components.

LCP1 antibodies are essential tools for studying immune cell dynamics and related pathologies. In research, these antibodies are used to detect LCP1 expression in immune cells via techniques like Western blotting, immunofluorescence, and flow cytometry. Dysregulated LCP1 expression has been implicated in autoimmune diseases, chronic inflammation, and cancer metastasis. For example, elevated LCP1 levels in certain cancers correlate with enhanced tumor cell invasiveness, making it a potential biomarker for metastatic progression. Additionally, LCP1 antibodies aid in exploring its role in immune signaling pathways and evaluating therapeutic strategies targeting cytoskeletal remodeling. Their specificity and reliability make them valuable for both basic immunology studies and clinical investigations.

       
關(guān)鍵字: LCP1抗體;LCP1;LCP1 Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學,細胞生物學 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

LCP1抗體—艾普蒂相關(guān)廠家報價

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