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KIF1C抗體,Rabbit Polyclonal KIF1C Antibody
  • KIF1C抗體,Rabbit Polyclonal KIF1C Antibody
  • KIF1C抗體,Rabbit Polyclonal KIF1C Antibody
  • KIF1C抗體,Rabbit Polyclonal KIF1C Antibody

KIF1C抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-19
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:KIF1C抗體英文名稱:Rabbit Polyclonal KIF1C Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4152 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: KIF1C
2025-05-19 KIF1C抗體 Rabbit Polyclonal KIF1C Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4152 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesSAX2; LTXS1; SATX2; SPAX2; SPG58
WB Predicted band size123 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human KIF1C
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: A549 cells, Primary antibody: P08461(KIF1C Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P08461(KIF1C Antibody) at dilution 1/60. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human sarcoma tissue using P08461(KIF1C Antibody) at dilution 1/60. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于KIF1C抗體的3篇參考文獻(xiàn)及其摘要內(nèi)容:

1. **文獻(xiàn)名稱**:*KIF1C regulates synaptic plasticity and cognition in mice through structural interaction with voltage-gated calcium channels*

**作者**:Li X, Zhang Y, Wang Y, et al.

**摘要**:該研究通過免疫共沉淀和免疫熒光技術(shù),利用KIF1C抗體揭示了KIF1C蛋白與電壓門控鈣通道的相互作用,證明其對小鼠突觸可塑性和認(rèn)知功能的調(diào)控作用,為神經(jīng)退行性疾病機(jī)制提供了新視角。

2. **文獻(xiàn)名稱**:*KIF1C modulates cancer cell migration and invasion by regulating focal adhesion dynamics*

**作者**:Dorahy DJ, Gu Q, Neufeld Z, et al.

**摘要**:研究采用KIF1C抗體進(jìn)行Western blot和免疫組化分析,發(fā)現(xiàn)KIF1C通過調(diào)控黏著斑動力學(xué)影響癌細(xì)胞遷移和侵襲能力,其表達(dá)水平與乳腺癌轉(zhuǎn)移潛力呈負(fù)相關(guān)。

3. **文獻(xiàn)名稱**:*Impaired mitochondrial transport in KIF1C-deficient neurons contributes to neurodegenerative pathology*

**作者**:van Bergeijk P, Adrian M, Hoogenraad CC, et al.

**摘要**:通過KIF1C抗體標(biāo)記神經(jīng)元中的線粒體運輸,研究發(fā)現(xiàn)KIF1C缺失導(dǎo)致線粒體分布異常,引發(fā)軸突能量供應(yīng)障礙,進(jìn)而加劇神經(jīng)退行性病變,提示KIF1C在神經(jīng)元穩(wěn)態(tài)中的關(guān)鍵作用。

(注:以上文獻(xiàn)信息為虛擬示例,實際引用需根據(jù)具體文獻(xiàn)調(diào)整。)

       

背景信息

KIF1C (Kinesin Family Member 1C) is a microtubule-dependent motor protein belonging to the kinesin superfamily, which plays critical roles in intracellular transport, organelle positioning, and cellular dynamics. It is encoded by the *KIF1C* gene and is involved in regulating vesicle trafficking, Golgi apparatus organization, and endoplasmic reticulum (ER) dynamics. KIF1C contains a conserved N-terminal motor domain that hydrolyzes ATP to generate mechanical force, enabling movement along microtubules. Studies link KIF1C to cellular processes such as autophagy, cell migration, and immune response modulation. Dysregulation of KIF1C has been implicated in diseases, including cancer, neurodegenerative disorders, and autoimmune conditions like rheumatoid arthritis.

KIF1C antibodies are immunological tools used to detect and study the expression, localization, and function of KIF1C in research. They are essential for techniques like Western blotting, immunofluorescence, and immunoprecipitation. These antibodies aid in exploring KIF1C's role in pathological mechanisms, such as tumor metastasis or synaptic dysfunction. Commercial KIF1C antibodies are typically raised in hosts like rabbits or mice, targeting specific epitopes, and require validation for specificity via knockout controls or siRNA-based approaches. Their applications span basic cell biology, disease biomarker research, and therapeutic target validation.

       
關(guān)鍵字: KIF1C抗體;KIF1C;KIF1C Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

KIF1C抗體—艾普蒂相關(guān)廠家報價

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2025-07-28
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2025-06-04
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