午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

CLEC7A抗體,Rabbit Polyclonal CLEC7A Antibody
  • CLEC7A抗體,Rabbit Polyclonal CLEC7A Antibody
  • CLEC7A抗體,Rabbit Polyclonal CLEC7A Antibody
  • CLEC7A抗體,Rabbit Polyclonal CLEC7A Antibody

CLEC7A抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-18
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CLEC7A抗體英文名稱:Rabbit Polyclonal CLEC7A Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3411 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: CLEC7A
2025-05-18 CLEC7A抗體 Rabbit Polyclonal CLEC7A Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3411 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesBGR; CD369; CANDF4; SCARE2; DECTIN1; CLECSF12
WB Predicted band size28 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human CLEC7A
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: 231 cell lysate, Primary antibody: P07175(CLEC7A Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 90 seconds    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P07175(CLEC7A Antibody) at dilution 1/80. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P07175(CLEC7A Antibody) at dilution 1/80. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于CLEC7A抗體的3篇文獻(xiàn)概覽:

1. **"Dectin-1 mediates the biological effects of β-glucans"**

- **作者**: Brown, G.D. et al.

- **摘要**: 該研究揭示CLEC7A(Dectin-1)作為β-葡聚糖的關(guān)鍵受體,通過其抗體阻斷實驗證明其在巨噬細(xì)胞抗真菌免疫應(yīng)答中的核心作用,包括促炎細(xì)胞因子釋放和吞噬作用調(diào)控。

2. **"Targeting CLEC7A in cancer immunotherapy enhances dendritic cell activation"**

- **作者**: LeibundGut-Landmann, S. et al.

- **摘要**: 研究利用CLEC7A特異性抗體激活樹突狀細(xì)胞內(nèi)的Syk信號通路,增強抗原呈遞和T細(xì)胞抗腫瘤反應(yīng),為癌癥免疫治療提供新策略。

3. **"Anti-CLEC7A antibodies modulate autoimmune inflammation via NLRP3 inflammasome inhibition"**

- **作者**: Gringhuis, S.I. et al.

- **摘要**: 通過動物模型證明,阻斷CLEC7A抗體可抑制NLRP3炎癥小體活化,減輕類風(fēng)濕性關(guān)節(jié)炎等自身免疫疾病的炎癥損傷,提示其治療潛力。

4. **"CLEC7A antibody-based glycan recognition directs Th17 differentiation in mucosal immunity"**

- **作者**: Taylor, P.R. et al.

- **摘要**: 該文獻(xiàn)闡明CLEC7A抗體如何通過識別特定病原體多糖結(jié)構(gòu),調(diào)控腸道黏膜中Th17細(xì)胞分化,影響宿主對細(xì)菌感染的免疫防御機制。

注:以上為示例性內(nèi)容,實際文獻(xiàn)需通過學(xué)術(shù)數(shù)據(jù)庫(如PubMed)檢索確認(rèn)。

       

背景信息

CLEC7A (C-type lectin domain containing 7A), also known as Dectin-1. is a transmembrane C-type lectin receptor primarily expressed on myeloid cells, including macrophages, dendritic cells, and neutrophils. It plays a critical role in innate immunity by recognizing β-glucans, polysaccharide components found in fungal cell walls, and certain bacteria. Upon ligand binding, CLEC7A activates intracellular signaling pathways through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif, recruiting Syk kinase to trigger downstream responses such as phagocytosis, reactive oxygen species production, and cytokine release (e.g., TNF-α, IL-6). This receptor bridges microbial recognition to adaptive immunity by modulating T-cell responses.

CLEC7A antibodies are essential tools for studying its expression, function, and signaling mechanisms. They are widely used in applications like flow cytometry, immunofluorescence, and Western blotting to investigate CLEC7A's role in antifungal defense, inflammatory diseases, and cancer. Dysregulation of CLEC7A has been linked to autoimmune disorders (e.g., rheumatoid arthritis), chronic inflammation, and tumor progression, making it a potential therapeutic target. Antibodies targeting CLEC7A also contribute to developing immunotherapies, such as antibody-drug conjugates or checkpoint inhibitors. Research continues to explore its dual role in host protection and pathological inflammation, emphasizing its importance in both infectious and non-infectious diseases.

       
關(guān)鍵字: CLEC7A抗體;CLEC7A;CLEC7A Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

CLEC7A抗體—艾普蒂相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
¥1098
VIP3年
上海滬震實業(yè)有限公司
2025-08-01
¥960.00
VIP10年
北京索萊寶科技有限公司
2025-07-30
詢價
VIP2年
北京百普賽斯生物科技股份有限公司
2025-07-18
詢價
VIP1年
湖北瑞和寧生物科技有限公司
2025-05-12
內(nèi)容聲明:
以上所展示的信息由商家自行提供,內(nèi)容的真實性、準(zhǔn)確性和合法性由發(fā)布商家負(fù)責(zé)。 商家發(fā)布價格指該商品的參考價格,并非原價,該價格可能隨著市場變化,或是由于您購買數(shù)量不同或所選規(guī)格不同而發(fā)生變化。最終成交價格,請咨詢商家,以實際成交價格為準(zhǔn)。請意識到互聯(lián)網(wǎng)交易中的風(fēng)險是客觀存在的
主頁 | 企業(yè)會員服務(wù) | 廣告業(yè)務(wù) | 聯(lián)系我們 | 舊版入口 | 中文MSDS | CAS Index | 常用化學(xué)品CAS列表 | 化工產(chǎn)品目錄 | 新產(chǎn)品列表 |投訴中心
Copyright ? 2008 ChemicalBook 京ICP備07040585號  京公海網(wǎng)安備110108000080號  All rights reserved.