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IFNA5抗體,Rabbit Polyclonal IFNA5 Antibody
  • IFNA5抗體,Rabbit Polyclonal IFNA5 Antibody
  • IFNA5抗體,Rabbit Polyclonal IFNA5 Antibody
  • IFNA5抗體,Rabbit Polyclonal IFNA5 Antibody

IFNA5抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-18
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:IFNA5抗體英文名稱:Rabbit Polyclonal IFNA5 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3236 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: IFNA5
2025-05-18 IFNA5抗體 Rabbit Polyclonal IFNA5 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3236 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC咨詢技術(shù) Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesT11; SRBC; LFA-2
Entrez GeneID914
clone3D1E3
WB Predicted band size39.4kDa
Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityMouse
ImmunogenPurified recombinant fragment of human CD2 (AA: 25-140) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide

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       Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)    


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       Western blot analysis using CD2 mouse mAb against MOLT4 (1), MCF-7 (2), L1210 (3), U937 (4), and NIH3T3 (5) cell lysate.    


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       Flow cytometric analysis of Hela cells using CD2 mouse mAb (green) and negative control (red).    


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       Flow cytometric analysis of HepG2 cells using CD2 mouse mAb (green) and negative control (red).    


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       Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CD2 mouse mAb with DAB staining.    


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       Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues using CD2 mouse mAb with DAB staining.    


           

參考文獻(xiàn)

以下是關(guān)于IFNA5抗體的假設(shè)性參考文獻(xiàn)示例(請注意,這些文獻(xiàn)為虛構(gòu)示例,實際引用需查詢真實數(shù)據(jù)庫):

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1. **文獻(xiàn)名稱**: *"Development of a Monoclonal Antibody Specific for Human IFNA5 and Its Application in Detecting Interferon Expression Profiles"*

**作者**: Smith A, et al.

**摘要**: 本研究開發(fā)了一種高特異性抗人IFNA5的單克隆抗體,用于區(qū)分IFNA5與其他I型干擾素亞型。通過ELISA和免疫組化驗證,該抗體成功應(yīng)用于病毒感染模型中IFNA5的蛋白表達(dá)定位,揭示了其在抗病毒反應(yīng)中的獨特表達(dá)模式。

2. **文獻(xiàn)名稱**: *"IFNA5 Neutralizing Antibody Attenuates Autoimmune Inflammation in a Murine Model"*

**作者**: Chen L, et al.

**摘要**: 文章報道了一種中和性IFNA5抗體在自身免疫性疾病模型中的應(yīng)用。實驗表明,阻斷IFNA5可顯著減少Th17細(xì)胞介導(dǎo)的炎癥反應(yīng),提示IFNA5可能成為治療類風(fēng)濕性關(guān)節(jié)炎等疾病的潛在靶點。

3. **文獻(xiàn)名稱**: *"Epitope Mapping of IFNA5 Using Polyclonal Antibodies Reveals Functional Domains"*

**作者**: Tanaka K, et al.

**摘要**: 通過多克隆抗體對IFNA5的表位進(jìn)行定位分析,發(fā)現(xiàn)其C端區(qū)域?qū)κ荏w結(jié)合至關(guān)重要。該研究為設(shè)計靶向IFNA5的抗體藥物提供了結(jié)構(gòu)生物學(xué)依據(jù)。

4. **文獻(xiàn)名稱**: *"Differential Expression of IFNA5 in Tumor Microenvironments Identified by Immunohistochemical Staining"*

**作者**: Müller R, et al.

**摘要**: 利用商業(yè)化IFNA5抗體對多種癌癥組織進(jìn)行染色,發(fā)現(xiàn)IFNA5在腫瘤相關(guān)成纖維細(xì)胞中高表達(dá),提示其可能通過調(diào)控腫瘤微環(huán)境影響免疫治療效果。

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**備注**:以上文獻(xiàn)為示例性質(zhì),實際研究中請通過PubMed、Web of Science等平臺檢索真實文獻(xiàn)(如搜索關(guān)鍵詞:IFNA5 antibody, interferon alpha 5 antibody)。若需具體文獻(xiàn)協(xié)助,建議提供更詳細(xì)的研究方向。

       

背景信息

The interferon alpha 5 (IFNA5) protein is a member of the type I interferon (IFN) family, which plays a critical role in innate immunity against viral infections and tumor surveillance. Encoded by the IFNA5 gene, it shares structural homology with other IFN-α subtypes but exhibits distinct receptor-binding affinities and downstream signaling activities. IFNA5 signals through the IFN-α/β receptor (IFNAR), activating JAK-STAT pathways to induce interferon-stimulated genes (ISGs) that mediate antiviral, antiproliferative, and immunomodulatory effects.

Antibodies targeting IFNA5 are essential tools for studying its expression, function, and regulation in both physiological and pathological contexts. They enable detection of IFNA5 in biological samples (e.g., ELISA, Western blot) and localization in tissues (e.g., immunohistochemistry). Such antibodies are particularly relevant in research on autoimmune diseases (e.g., lupus), viral infections, and cancers, where dysregulated IFN signaling is implicated. Additionally, neutralizing IFNA5 antibodies may have therapeutic potential for mitigating IFN-driven pathologies. Commercial IFNA5 antibodies vary in specificity (monoclonal vs. polyclonal), host species, and applications, requiring validation to avoid cross-reactivity with other IFN-α subtypes. Recent studies also explore IFNA5's unique role in tumor microenvironments and its biomarker potential, underscoring the importance of reliable antibody reagents in advancing IFN-related research.

       
關(guān)鍵字: IFNA5抗體;IFNA5;IFNA5 Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

IFNA5抗體—艾普蒂相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
詢價
VIP3年
武漢佰樂博生物技術(shù)有限公司
2025-08-01
¥3500
VIP4年
上海博爾森生物科技有限公司
2025-08-01
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
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