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GAS2L1抗體,Rabbit Polyclonal GAS2L1 Antibody
  • GAS2L1抗體,Rabbit Polyclonal GAS2L1 Antibody
  • GAS2L1抗體,Rabbit Polyclonal GAS2L1 Antibody
  • GAS2L1抗體,Rabbit Polyclonal GAS2L1 Antibody

GAS2L1抗體—艾普蒂

價(jià)格 詢(xún)價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-18
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產(chǎn)品詳情

中文名稱(chēng):GAS2L1抗體英文名稱(chēng):Rabbit Polyclonal GAS2L1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 2966 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類(lèi)別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): GAS2L1
2025-05-18 GAS2L1抗體 Rabbit Polyclonal GAS2L1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 2966 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢(xún)技術(shù) Human,Mouse,Rat
IF咨詢(xún)技術(shù) Human,Mouse,Rat
IHC1/10-1/50 Human,Mouse,Rat
ICC技術(shù)咨詢(xún) Human,Mouse,Rat
FCM咨詢(xún)技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesGAR22
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human GAS2L1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P05861(GAS2L1 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于GAS2L1抗體的3篇參考文獻(xiàn)示例(注:以下文獻(xiàn)為虛構(gòu)示例,實(shí)際文獻(xiàn)需通過(guò)學(xué)術(shù)數(shù)據(jù)庫(kù)檢索確認(rèn)):

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1. **標(biāo)題**: "GAS2L1 modulates cytoskeletal dynamics during cytokinesis through antibody-based localization studies"

**作者**: Bennin, D.A., et al.

**摘要**: 本研究利用特異性GAS2L1抗體,揭示其在哺乳動(dòng)物細(xì)胞胞質(zhì)分裂中的關(guān)鍵作用。通過(guò)免疫熒光實(shí)驗(yàn)發(fā)現(xiàn),GAS2L1通過(guò)與微管和肌動(dòng)蛋白結(jié)合,調(diào)控收縮環(huán)的穩(wěn)定性。

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2. **標(biāo)題**: "GAS2L1 as a potential biomarker in colorectal cancer: Immunohistochemical analysis using a novel monoclonal antibody"

**作者**: Zhang, Y., et al.

**摘要**: 開(kāi)發(fā)了一種高特異性抗GAS2L1單克隆抗體,用于結(jié)直腸癌組織分析。結(jié)果顯示,GAS2L1表達(dá)水平與腫瘤侵襲性和患者預(yù)后顯著相關(guān),提示其作為診斷標(biāo)志物的潛力。

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3. **標(biāo)題**: "The role of GAS2L1 in microtubule stabilization and its interaction with tau protein revealed by co-immunoprecipitation"

**作者**: Li, X., et al.

**摘要**: 通過(guò)GAS2L1抗體進(jìn)行免疫共沉淀實(shí)驗(yàn),發(fā)現(xiàn)GAS2L1通過(guò)穩(wěn)定微管網(wǎng)絡(luò)影響神經(jīng)元形態(tài),并與tau蛋白存在功能關(guān)聯(lián),為神經(jīng)退行性疾病機(jī)制研究提供新方向。

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如需真實(shí)文獻(xiàn),建議在 **PubMed** 或 **Google Scholar** 檢索關(guān)鍵詞:

`GAS2L1 antibody`、`GAS2L1 function`、`GAS2L1 biomarker`。

       

背景信息

The GAS2L1 (Growth Arrest-Specific 2 Like 1) antibody is a tool used to study the GAS2L1 protein, a member of the GAS2 family involved in regulating cytoskeletal dynamics and cell cycle progression. GAS2L1 contains conserved domains (CH, GAR) that enable interactions with microtubules and microfilaments, playing a role in mitotic spindle organization and chromosome segregation during cell division. Research highlights its importance in maintaining genomic stability, with dysregulation linked to mitotic errors and cancer progression, such as glioblastoma and hepatocellular carcinoma.

This antibody is widely employed in techniques like Western blotting, immunofluorescence, and immunoprecipitation to detect GAS2L1 expression, localization, and interactions. Studies using the antibody have revealed its cell cycle-dependent expression, peaking during mitosis, and its role in cellular stress responses, including DNA damage repair. Notably, GAS2L1 knockdown experiments (supported by antibody validation) demonstrate its necessity for proper spindle assembly and chromosome alignment. Recent work also implicates GAS2L1 in neurodevelopmental processes and ciliogenesis. As an emerging biomarker and therapeutic target, the GAS2L1 antibody remains critical for unraveling its dual roles in physiological homeostasis and disease mechanisms.

       
關(guān)鍵字: GAS2L1抗體;GAS2L1;GAS2L1 Antibody;

公司簡(jiǎn)介

是一家科研、開(kāi)發(fā)、生產(chǎn)和銷(xiāo)售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊(cè)資本 20萬(wàn)人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以?xún)?nèi)
主營(yíng)行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類(lèi)型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
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