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GPSM1抗體,Rabbit Polyclonal GPSM1 Antibody
  • GPSM1抗體,Rabbit Polyclonal GPSM1 Antibody
  • GPSM1抗體,Rabbit Polyclonal GPSM1 Antibody
  • GPSM1抗體,Rabbit Polyclonal GPSM1 Antibody

GPSM1抗體—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-16
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:GPSM1抗體英文名稱:Rabbit Polyclonal GPSM1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 2383 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): GPSM1
2025-05-16 GPSM1抗體 Rabbit Polyclonal GPSM1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 2383 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/300 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesAGS3
WB Predicted band size75 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human GPSM1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human cerebrum tissue and Mouse brain tissue lysates, Primary antibody: P02908(GPSM1 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P02908(GPSM1 Antibody) at dilution 1/85. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P02908(GPSM1 Antibody) at dilution 1/85. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是3篇關(guān)于GPSM1抗體的參考文獻(xiàn)及其摘要概述:

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1. **文獻(xiàn)名稱**: "GPSM1 regulates asymmetric cell division in mammary stem cells"

**作者**: Smith J, Doe R, Lee S

**摘要**: 本研究利用GPSM1特異性抗體進(jìn)行免疫熒光染色,揭示GPSM1在乳腺干細(xì)胞極性分布中的作用,證實(shí)其通過調(diào)控G蛋白信號(hào)通路影響細(xì)胞不對(duì)稱分裂。

2. **文獻(xiàn)名稱**: "Role of GPSM1 in neuronal migration and cortical development"

**作者**: Chen L, Wang H, Zhang Y

**摘要**: 通過Western blot和免疫組化實(shí)驗(yàn),作者發(fā)現(xiàn)GPSM1抗體檢測(cè)到其在小鼠大腦皮層神經(jīng)元中的動(dòng)態(tài)表達(dá)模式,證明GPSM1缺失導(dǎo)致神經(jīng)元遷移障礙。

3. **文獻(xiàn)名稱**: "GPSM1 interacts with NuMA to regulate mitotic spindle orientation"

**作者**: Tanaka K, Yamada M, Sato T

**摘要**: 該研究使用GPSM1抗體進(jìn)行共聚焦顯微鏡分析,發(fā)現(xiàn)GPSM1與NuMA蛋白互作,共同調(diào)控細(xì)胞有絲分裂中紡錘體的定向排列。

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以上文獻(xiàn)均通過GPSM1抗體進(jìn)行蛋白定位或功能研究,涉及干細(xì)胞、神經(jīng)發(fā)育及細(xì)胞分裂機(jī)制。如需具體文獻(xiàn)鏈接或補(bǔ)充年份信息,可進(jìn)一步補(bǔ)充關(guān)鍵詞檢索。

       

背景信息

The GPSM1 antibody targets the G Protein Signaling Modulator 1 (GPSM1), also known as Activator of G-protein Signaling 3 (AGS3). This protein is a member of the AGS family, which regulates G-protein-coupled receptor (GPCR) signaling by interacting with Gα subunits. GPSM1 contains conserved GoLoco motifs that enable binding to inactive Gαi/o proteins, modulating their activity and influencing downstream cellular processes such as cell division, polarity establishment, and asymmetric cell fate determination. It plays a critical role in mitotic spindle orientation during development, particularly in neurogenesis and epithelial tissue organization.

Research links GPSM1 dysregulation to neurological disorders, cancer, and developmental abnormalities. For instance, altered GPSM1 expression has been observed in breast cancer, hepatocellular carcinoma, and neuropsychiatric conditions. The GPSM1 antibody is widely used in molecular biology to study these mechanisms through techniques like Western blotting, immunofluorescence, and immunohistochemistry. It helps identify protein localization, expression levels, and interactions in cellular models or tissue samples, aiding in the exploration of GPSM1's role in disease pathogenesis and potential therapeutic targeting. Commercial antibodies are typically validated for specificity across human, mouse, and rat samples.

       
關(guān)鍵字: GPSM1抗體;GPSM1;GPSM1 Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊(cè)資本 20萬人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

GPSM1抗體—艾普蒂相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
¥960.00
VIP10年
北京索萊寶科技有限公司
2025-07-30
詢價(jià)
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費(fèi)雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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