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NUBP2抗體,Rabbit Polyclonal NUBP2 Antibody
  • NUBP2抗體,Rabbit Polyclonal NUBP2 Antibody
  • NUBP2抗體,Rabbit Polyclonal NUBP2 Antibody
  • NUBP2抗體,Rabbit Polyclonal NUBP2 Antibody

NUBP2抗體—艾普蒂

價(jià)格 詢(xún)價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-16
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產(chǎn)品詳情

中文名稱(chēng):NUBP2抗體英文名稱(chēng):Rabbit Polyclonal NUBP2 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 2281 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類(lèi)別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): NUBP2
2025-05-16 NUBP2抗體 Rabbit Polyclonal NUBP2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 2281 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢(xún)技術(shù) Human,Mouse,Rat
IF咨詢(xún)技術(shù) Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢(xún) Human,Mouse,Rat
FCM咨詢(xún)技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesCFD1; NBP 2; NUBP1
WB Predicted band size29 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human Bladder transitional cell carcinoma grade 2-3 tissue lysate, Primary antibody: P02637(NUBP2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P02637(NUBP2 Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P02637(NUBP2 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于NUBP2抗體的3篇示例參考文獻(xiàn)(注:文獻(xiàn)為虛擬示例,建議通過(guò)學(xué)術(shù)數(shù)據(jù)庫(kù)檢索真實(shí)研究):

---

1. **文獻(xiàn)名稱(chēng)**: *NUBP2 regulates mitotic progression through interaction with the cytoskeleton*

**作者**: Smith J, et al. (2016)

**摘要**: 本研究利用NUBP2抗體進(jìn)行免疫印跡和免疫熒光實(shí)驗(yàn),發(fā)現(xiàn)NUBP2通過(guò)調(diào)控微管動(dòng)力學(xué)參與有絲分裂進(jìn)程,敲低NUBP2導(dǎo)致染色體排列異常。

2. **文獻(xiàn)名稱(chēng)**: *NUBP2 modulates iron-sulfur cluster biogenesis in human cells*

**作者**: Zhang L, et al. (2018)

**摘要**: 通過(guò)NUBP2抗體的免疫共沉淀(Co-IP)實(shí)驗(yàn),揭示NUBP2與線(xiàn)粒體鐵硫簇組裝蛋白ISCU的相互作用,證實(shí)其在細(xì)胞鐵代謝中的關(guān)鍵作用。

3. **文獻(xiàn)名稱(chēng)**: *Overexpression of NUBP2 correlates with poor prognosis in colorectal cancer*

**作者**: Tanaka K, et al. (2020)

**摘要**: 采用NUBP2抗體對(duì)結(jié)直腸癌組織進(jìn)行免疫組化分析,發(fā)現(xiàn)NUBP2高表達(dá)與腫瘤轉(zhuǎn)移及患者生存率降低顯著相關(guān),提示其作為癌癥標(biāo)志物的潛力。

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建議通過(guò)PubMed或Google Scholar以關(guān)鍵詞“NUBP2 antibody”、“NUBP2 function”檢索最新研究。

       

背景信息

The NUBP2 (Nucleotide-Binding Protein 2) antibody is a tool used to study the NUBP2 protein, a member of the cytosolic iron-sulfur cluster assembly (CIA) machinery. NUBP2. along with its homolog NUBP1. forms a heterotetrameric complex critical for the maturation and transfer of iron-sulfur (Fe-S) clusters to target apoproteins, which are essential for diverse cellular processes, including DNA repair, enzyme catalysis, and mitochondrial function. Dysregulation of NUBP2 has been implicated in diseases such as cancer and neurodegenerative disorders, where Fe-S cluster biogenesis is compromised.

The NUBP2 antibody is typically developed in hosts like rabbits or mice using immunogenic peptides or recombinant protein fragments. It is widely employed in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect NUBP2 expression levels, localization, and interactions in cell lines or tissues. Researchers use this antibody to explore NUBP2's role in cellular proliferation, redox homeostasis, and mitochondrial dynamics. Specificity is validated via knockout/knockdown controls or siRNA experiments. Commercial NUBP2 antibodies are often accompanied by validation data (e.g., species reactivity, application suitability) to ensure reproducibility. Studies utilizing this antibody have contributed to understanding molecular mechanisms underlying cancer progression, particularly in contexts where Fe-S cluster deficiency drives genomic instability or metabolic reprogramming.

       
關(guān)鍵字: NUBP2抗體;NUBP2;NUBP2 Antibody;

公司簡(jiǎn)介

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主營(yíng)行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠(chǎng),試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類(lèi)型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
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