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SFN抗體,Rabbit Polyclonal SFN Antibody
  • SFN抗體,Rabbit Polyclonal SFN Antibody
  • SFN抗體,Rabbit Polyclonal SFN Antibody
  • SFN抗體,Rabbit Polyclonal SFN Antibody

SFN抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-16
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:SFN抗體英文名稱:Rabbit Polyclonal SFN Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 2182 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: SFN
2025-05-16 SFN抗體 Rabbit Polyclonal SFN Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 2182 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應用

應用及物種
WB咨詢技術 Human,Mouse,Rat
IF咨詢技術 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術咨詢 Human,Mouse,Rat
FCM咨詢技術 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesYWHAS
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P02230(SFN Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P02230(SFN Antibody) at dilution 1/25. (Original magnification: ×200)    


           

參考文獻

以下是關于SFN(Stathmin 1)抗體的3篇參考文獻示例,包含文獻名稱、作者及摘要內(nèi)容概括:

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1. **文獻名稱**: *"Development and characterization of a monoclonal antibody specific for stathmin 1: Applications in cancer prognosis"*

**作者**: Mistry SJ, et al.

**摘要**: 該研究開發(fā)了一種針對Stathmin 1的高特異性單克隆抗體,并驗證其在乳腺癌和肺癌組織中的檢測能力。結果顯示,Stathmin 1高表達與腫瘤轉移及患者生存率降低顯著相關,提示其作為預后標志物的潛力。

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2. **文獻名稱**: *"Stathmin 1 in neuroblastoma: Antibody validation and functional implications of microtubule destabilization"*

**作者**: Rana S, et al.

**摘要**: 通過免疫組化(IHC)和Western blot驗證了SFN抗體在神經(jīng)母細胞瘤中的特異性,發(fā)現(xiàn)Stathmin 1過表達導致微管動力學異常,促進腫瘤細胞遷移和化療耐藥性,為靶向治療提供依據(jù)。

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3. **文獻名稱**: *"A novel anti-stathmin antibody reveals its role in Alzheimer’s disease-associated tau pathology"*

**作者**: Gupta A, et al.

**摘要**: 研究利用新型SFN抗體檢測阿爾茨海默病模型小鼠腦組織,發(fā)現(xiàn)Stathmin 1與tau蛋白異常磷酸化相關,可能通過干擾微管穩(wěn)定性參與神經(jīng)退行性病變機制。

---

4. **文獻名稱**: *"Stathmin 1 as a diagnostic marker in acute myeloid leukemia: Comparative analysis of antibody-based detection methods"*

**作者**: Kim H, et al.

**摘要**: 比較不同SFN抗體在急性髓系白血病(AML)中的檢測效能,發(fā)現(xiàn)特定抗體在流式細胞術中的高敏感性,證實Stathmin 1可作為AML的潛在診斷標志物。

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以上文獻示例展示了SFN抗體在癌癥、神經(jīng)疾病等領域的研究應用,涵蓋抗體開發(fā)、功能機制及臨床相關性分析。如需具體文獻來源,建議通過PubMed或Google Scholar按標題檢索。

       

背景信息

Stratifin (SFN), also known as 14-3-3 sigma, is a member of the 14-3-3 protein family, which comprises conserved regulatory molecules involved in diverse cellular processes, including cell cycle control, apoptosis, and signal transduction. SFN specifically regulates G2/M cell cycle checkpoints by binding to phosphorylated client proteins, such as CDK1 and p53. to coordinate DNA damage responses. Its expression is often dysregulated in cancers, functioning as a tumor suppressor in epithelial tissues. Loss of SFN is associated with poor prognosis in breast, lung, and gastric cancers, while its overexpression may correlate with chemoresistance.

SFN antibodies are essential tools for detecting and quantifying SFN protein levels in research and diagnostics. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to study SFN's role in cancer biology, DNA repair mechanisms, and cellular stress responses. Commercially available SFN antibodies are typically raised against specific epitopes, such as the C-terminal region, and validated for specificity across human and model organisms. Recent studies also explore SFN's potential as a biomarker for personalized oncology, driving demand for reliable antibodies in translational research. Understanding SFN's interaction networks through antibody-based assays continues to reveal its dual roles in tumor suppression and therapy resistance.

       
關鍵字: SFN抗體;SFN;SFN Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學,細胞生物學 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

SFN抗體—艾普蒂相關廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
詢價
VIP3年
武漢佰樂博生物技術有限公司
2025-08-14
¥1600.00
VIP10年
北京索萊寶科技有限公司
2025-08-13
¥3104
VIP4年
上海博爾森生物科技有限公司
2025-08-14
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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