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NAPA抗體,Rabbit Polyclonal NAPA Antibody
  • NAPA抗體,Rabbit Polyclonal NAPA Antibody
  • NAPA抗體,Rabbit Polyclonal NAPA Antibody
  • NAPA抗體,Rabbit Polyclonal NAPA Antibody

NAPA抗體

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-13
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:NAPA抗體英文名稱:Rabbit Polyclonal NAPA Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3635 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): NAPA
2025-05-13 NAPA抗體 Rabbit Polyclonal NAPA Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3635 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB1/500-1/2000 Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesSNAPA
WB Predicted band size33 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human NAPA
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hela cells, Jurkat cells, human liver cancer tissue, mouse brain tissue, Primary antibody: P07605(NAPA Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07605(NAPA Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07605(NAPA Antibody) at dilution 1/25. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于NAPA(α-SNAP)抗體的參考文獻(xiàn)示例(注:文獻(xiàn)為假設(shè)性示例,實(shí)際文獻(xiàn)需通過學(xué)術(shù)數(shù)據(jù)庫檢索確認(rèn)):

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1. **文獻(xiàn)名稱**: "Role of α-SNAP in Regulating Neurotransmitter Release"

**作者**: Martin, T.F., et al.

**摘要**: 研究α-SNAP蛋白在突觸囊泡融合中的作用,利用特異性抗體驗(yàn)證其在神經(jīng)分泌中的功能,揭示其與SNARE復(fù)合物的相互作用機(jī)制。

2. **文獻(xiàn)名稱**: "Altered Expression of α-SNAP in Diabetic Mouse Models"

**作者**: Sugawara, K., et al.

**摘要**: 通過免疫組化和Western blot分析,發(fā)現(xiàn)糖尿病模型中α-SNAP表達(dá)水平下降,提示其可能與胰島素分泌異常相關(guān)。

3. **文獻(xiàn)名稱**: "Development of a High-Affinity Monoclonal Antibody for α-SNAP Detection"

**作者**: Hsu, S.C., et al.

**摘要**: 描述一種新型抗α-SNAP單克隆抗體的制備方法,驗(yàn)證其在細(xì)胞成像和蛋白質(zhì)相互作用研究中的高特異性和靈敏度。

4. **文獻(xiàn)名稱**: "α-SNAP Dysfunction in Immune Cell Vesicle Trafficking"

**作者**: Brown, A.M., et al.

**摘要**: 探究α-SNAP抗體在巨噬細(xì)胞吞噬作用研究中的應(yīng)用,揭示其在免疫細(xì)胞囊泡運(yùn)輸中的關(guān)鍵調(diào)控作用。

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**注意**:以上文獻(xiàn)為示例性質(zhì),實(shí)際研究中請(qǐng)通過PubMed、Google Scholar等平臺(tái)檢索關(guān)鍵詞(如"α-SNAP antibody"、"NAPA protein")獲取最新研究成果。

       

背景信息

NAPA (NSF Attachment Protein Alpha), also known as α-SNAP, is a critical component of intracellular vesicle trafficking and membrane fusion processes. It belongs to the SNAP family of soluble proteins that interact with the SNARE (Soluble NSF Attachment Protein Receptor) complex, which mediates the fusion of transport vesicles with target membranes. NAPA binds to the SNARE complex and recruits NSF (N-ethylmaleimide-sensitive fusion protein), an ATPase essential for disassembling SNAREs after fusion, thereby recycling them for subsequent rounds of membrane docking. This mechanism is vital for neurotransmitter release, organelle biogenesis, and protein secretion.

Antibodies targeting NAPA are widely used in biomedical research to study vesicular transport dynamics, synaptic function, and cellular secretion pathways. They enable the detection, localization, and quantification of NAPA in various experimental models, including immunoprecipitation, Western blotting, and immunofluorescence microscopy. Dysregulation of NAPA has been implicated in neurological disorders, such as epilepsy and neurodegenerative diseases, as well as in cancer progression due to its role in regulating cell proliferation and apoptosis. Research utilizing NAPA antibodies has provided insights into pathological mechanisms and potential therapeutic targets. These antibodies thus serve as essential tools for elucidating the molecular basis of vesicle trafficking and its implications in health and disease.

       
關(guān)鍵字: NAPA抗體;NAPA;NAPA Antibody;

公司簡(jiǎn)介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國(guó)內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊(cè)資本 50萬(元)
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營(yíng)行業(yè) 中間體,化學(xué)試劑 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:50萬(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

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2025-08-07
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VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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