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NTF4抗體,Rabbit Polyclonal NTF4 Antibody
  • NTF4抗體,Rabbit Polyclonal NTF4 Antibody
  • NTF4抗體,Rabbit Polyclonal NTF4 Antibody
  • NTF4抗體,Rabbit Polyclonal NTF4 Antibody

NTF4抗體

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-13
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:NTF4抗體英文名稱:Rabbit Polyclonal NTF4 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3571 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): NTF4
2025-05-13 NTF4抗體 Rabbit Polyclonal NTF4 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3571 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB1/500-1/2000 Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/10-1/50 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesNT4, NT5, NT-4, NT-5, NTF5, GLC10, GLC1O, NT-4/5
WB Predicted band size22 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human NTF4
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: 231 cells, Primary antibody: P07498(NTF4 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07498(NTF4 Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P07498(NTF4 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于NTF4抗體的3篇示例文獻(xiàn)概覽(內(nèi)容為虛構(gòu)示例,僅供格式參考):

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1. **"Development and validation of a high-affinity monoclonal antibody against human Neurotrophin-4 (NTF4)"**

*Author: Lee, J. et al.*

摘要:本研究報(bào)道了一種新型NTF4單克隆抗體的開發(fā),通過雜交瘤技術(shù)篩選出高特異性抗體,并通過ELISA、Western blot和免疫組化驗(yàn)證其在人腦組織中的結(jié)合能力。該抗體可用于神經(jīng)退行性疾病中NTF4蛋白表達(dá)的定量檢測(cè)。

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2. **"NTF4 antibody-based therapeutic targeting in Alzheimer's disease models"**

*Author: Rodriguez, S. et al.*

摘要:文章探討了NTF4抗體在阿爾茨海默病小鼠模型中的治療潛力。實(shí)驗(yàn)表明,抗體可通過血腦屏障中和異常聚集的NTF4蛋白,減少神經(jīng)元凋亡并改善認(rèn)知功能,提示其作為神經(jīng)保護(hù)劑的潛在應(yīng)用。

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3. **"Structural mapping of NTF4 epitopes using phage display technology"**

*Author: Gupta, R. & Wang, T.*

摘要:通過噬菌體展示技術(shù)解析NTF4抗體的抗原表位,發(fā)現(xiàn)抗體主要結(jié)合于NTF4蛋白的β-折疊區(qū)域。該研究為優(yōu)化抗體親和力及設(shè)計(jì)靶向藥物提供了結(jié)構(gòu)基礎(chǔ)。

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注:以上文獻(xiàn)為模擬示例,實(shí)際引用需通過PubMed或Web of Science等數(shù)據(jù)庫檢索真實(shí)研究。如需具體文獻(xiàn)推薦,建議補(bǔ)充研究領(lǐng)域或應(yīng)用場(chǎng)景(如疾病、實(shí)驗(yàn)方法等)。

       

背景信息

Neurotrophin-4 (NTF4), also known as NT-4 or NT-5 depending on species, is a member of the neurotrophin family of growth factors that play critical roles in neuronal survival, development, and plasticity. It binds to the tropomyosin receptor kinase B (TrkB) and the low-affinity p75 neurotrophin receptor, activating downstream signaling pathways involved in synaptic modulation, axon guidance, and cell differentiation. NTF4 is expressed in both the central and peripheral nervous systems and has been implicated in processes such as memory formation, pain regulation, and recovery from neural injury. Dysregulation of NTF4 signaling has been linked to neurodegenerative diseases (e.g., Alzheimer’s), mood disorders, and neuropathic pain.

Antibodies targeting NTF4 are essential tools for studying its expression, localization, and function in biological systems. They are widely used in techniques like Western blotting, immunohistochemistry, and ELISA to quantify protein levels or visualize distribution in tissues. Commercial NTF4 antibodies are typically raised in hosts such as rabbits or mice using recombinant protein fragments or synthetic peptides. However, challenges remain in ensuring specificity due to high homology among neurotrophin family members. Recent research emphasizes the need for rigorous validation via knockout controls or neutralization assays. Such antibodies have advanced understanding of NTF4's role in neuroprotection and its potential as a therapeutic target, particularly in conditions involving neuronal degeneration or synaptic dysfunction.

       
關(guān)鍵字: NTF4抗體;NTF4;NTF4 Antibody;

公司簡(jiǎn)介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊(cè)資本 50萬(元)
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學(xué)試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:50萬(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

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NTF4抗體相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
詢價(jià)
VIP3年
武漢佰樂博生物技術(shù)有限公司
2025-07-31
¥960.00
VIP10年
北京索萊寶科技有限公司
2025-07-30
詢價(jià)
VIP3年
維百奧(北京)生物科技有限公司
2025-07-30
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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