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TEKT1抗體,Rabbit Polyclonal TEKT1 Antibody
  • TEKT1抗體,Rabbit Polyclonal TEKT1 Antibody
  • TEKT1抗體,Rabbit Polyclonal TEKT1 Antibody
  • TEKT1抗體,Rabbit Polyclonal TEKT1 Antibody

TEKT1抗體

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-11
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:TEKT1抗體英文名稱:Rabbit Polyclonal TEKT1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 1764 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): TEKT1
2025-05-11 TEKT1抗體 Rabbit Polyclonal TEKT1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 1764 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

WB Predicted band size48 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human TEKT1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

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       Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: NIH/3T3 cells, Lncap cells, Primary antibody: P00745(TEKT1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human lymphoma tissue using P00745(TEKT1 Antibody) at dilution 1/30. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P00745(TEKT1 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于TEKT1抗體的3篇示例參考文獻(xiàn),內(nèi)容基于學(xué)術(shù)文獻(xiàn)的常見結(jié)構(gòu)模擬,僅供參考:

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1. **標(biāo)題**: *"Tektin-1 (TEKT1) Localization in Sperm Flagella and Its Role in Motility"*

**作者**: Smith J, Lee A, et al.

**摘要**: 本研究利用特異性TEKT1抗體,通過免疫熒光技術(shù)揭示了TEKT1蛋白在人類精子鞭毛中的定位。實(shí)驗(yàn)發(fā)現(xiàn),TEKT1缺失或突變會(huì)導(dǎo)致精子運(yùn)動(dòng)能力顯著下降,提示其在鞭毛結(jié)構(gòu)和功能中的關(guān)鍵作用。該抗體為男性不育癥研究提供了重要工具。

2. **標(biāo)題**: *"Development and Validation of a Polyclonal Antibody Against Human TEKT1 for Cancer Biomarker Studies"*

**作者**: Chen L, Wang Y, et al.

**摘要**: 研究團(tuán)隊(duì)成功制備了針對(duì)人源TEKT1的多克隆抗體,并通過Western blot和免疫組化驗(yàn)證其特異性。在肺癌組織樣本中,TEKT1表達(dá)顯著上調(diào),且與患者預(yù)后不良相關(guān)??贵w在癌癥診斷和機(jī)制研究中的潛在應(yīng)用被進(jìn)一步探討。

3. **標(biāo)題**: *"TEKT1 Deficiency Disrupts Ciliary Function in Murine Models: Insights from Antibody-Based Imaging"*

**作者**: Gupta R, Tanaka H, et al.

**摘要**: 通過TEKT1抗體介導(dǎo)的免疫染色技術(shù),本研究在小鼠模型中觀察到TEKT1缺失導(dǎo)致纖毛結(jié)構(gòu)異常和呼吸道功能障礙。結(jié)果強(qiáng)調(diào)了TEKT1在纖毛相關(guān)疾病(如原發(fā)性纖毛運(yùn)動(dòng)障礙)中的病理意義,抗體在此類疾病模型中具有重要研究?jī)r(jià)值。

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**注**:以上文獻(xiàn)為模擬示例,實(shí)際研究中請(qǐng)通過學(xué)術(shù)數(shù)據(jù)庫(如PubMed、Web of Science)檢索真實(shí)發(fā)表的論文。

       

背景信息

TEKT1 (tektin-1) is a member of the tektin family of filamentous proteins, which are integral components of microtubule-based structures such as cilia, flagella, and centrioles. Predominantly expressed in the testis, TEKT1 is localized to the outer dense fibers of sperm flagella, playing a critical role in maintaining structural integrity and facilitating sperm motility. Its function is closely linked to male fertility, as mutations or dysregulation of TEKT1 have been associated with asthenozoospermia (reduced sperm motility) and infertility.

TEKT1 antibodies are valuable tools for studying sperm development, ciliary biology, and reproductive disorders. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to detect TEKT1 expression, localization, and potential abnormalities in clinical or research samples. Beyond reproductive health, emerging studies suggest TEKT1 may have roles in certain cancers (e.g., gliomas) where ciliary dysfunction is implicated. These antibodies also aid in exploring TEKT1's interactions with other cytoskeletal proteins, providing insights into microtubule dynamics and cellular mechanobiology. Commercial TEKT1 antibodies are typically raised in rabbits or mice, with validation in human and model organisms, supporting both diagnostic and basic research applications.

       
關(guān)鍵字: TEKT1抗體;TEKT1;TEKT1 Antibody;

公司簡(jiǎn)介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國(guó)內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊(cè)資本 50萬(元)
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營(yíng)行業(yè) 中間體,化學(xué)試劑 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:50萬(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

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TEKT1抗體相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
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2025-07-28
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