Rabbit Anti-CRISP3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CRISP3
IR:Immunogen Range:21-120/245
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10321
Swiss Prot:P54108
Source:KLH conjugated synthetic peptide derived from human CRISP3:21-120/245
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. AEG is a sperm surface protein involved in the fusion of egg and sperm. Although CRISP-1 (also designated AEG-like protein, ARP, cysteine-rich secretory protein-1 or AEG-related protein) is not the ortholog of rodent AEG, it resembles AEG in that it is an epididymal secretory glycoprotein that binds to the postacrosomal region of the sperm head. CRISP-1 coats the postacrosomal region of sperm heads as they pass through the epididymis. CRISP-1 is found in all regions of the epididymis, ductus deferens, seminal plasma and sperm. CRISP-3 is expressed in pancreas and prostate tissues and, along with CRISP-1, is expressed in saliva. The gene that encodes CRISP-3 is an early response gene that may participate in the pathophysiology of the autoimmune lesions of Sjogren’s syndrome.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Rabbit
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： CRISP3;Aeg2;CRISP-3;CRS3;Cysteine rich secret;SGP28;SGP28 protein;CRIS3_HUMAN;
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