Rabbit Anti-NR2D Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:NR2D
IR:Immunogen Range:601-600/1336
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2906
Swiss Prot:O15399
Source:KLH conjugated synthetic peptide derived from human NR2D:601-600/1336
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:NR2D is a NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. NR2D is expressed in the brain; it is detected in embryonic stages, peaks at postnatal day 7, and decreases thereafter to adult levels.
[FUNCTION] NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. [SUBUNIT] Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Interacts with PDZ domains of INADL and DLG4. [SUBCELLULAR LOCATION] Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. [TISSUE SPECIFICITY] Expressed in brain, mainly in the subcortical region. [SIMILARITY] Belongs to the glutamate-gated ion channel
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
Flow-Cyt(3ug/test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： NR2D;Glutamate [NMDA] rec;Grin2d;N-methyl D-aspartate;NMDAR2D;NMDE4;NR2D;NMDE4_HUMAN;
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