Rabbit Anti-EDG1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:EDG1
IR:Immunogen Range:51-150/382
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1901
Swiss Prot:P21453
Source:KLH conjugated synthetic peptide derived from human EDG1/CD363:51-150/382
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 is a G-protein-coupled receptor which binds the bioactive signaling molecule sphingosine 1-phosphate (S1P). S1PR1 belongs to a sphingosine-1-phosphate receptor subfamily comprising five members (S1PR1-5). S1PR1 was originally identified as an abundant transcript in endothelial cells and it has an important role in regulating endothelial cell cytoskeletal structure, migration, capillary-like network formation and vascular maturation. In addition, S1PR1 signaling is important in the regulation of lymphocyte maturation, migration and trafficking.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： EDG1;CD363;CHEDG1;D1S3362;ECGF1;EDG1;S1PR1;S1PR1_HUMAN;
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