L-Tryptophan suppliers
L-Tryptophan
- CAS:
- 73-22-3
- MF:
- C11H12N2O2
- MW:
- 204.23
Suppliers by country/region
- Bangladesh(1)
- CHINA(478)
- United States(140)
- India(60)
- Germany(26)
- United Kingdom(35)
- Canada(14)
- France(4)
- Japan(10)
- Switzerland(11)
- Slovakia(2)
- Europe(3)
- Hungary(2)
- Ukraine(2)
- Belgium(4)
- Poland(4)
- Italy(2)
- Spain(6)
- Ireland(1)
- Mexico(1)
- Czech Republic(2)
- The Netherlands(3)
- Brazil(1)
- Australia(1)
- Egypt(1)
- South Korea(3)
- Slovenia(1)
Company Type
Properties
- Melting point:
- 289-290 °C (dec.)(lit.)
- Boiling point:
- 342.72°C (rough estimate)
- alpha
- -31.1 º (c=1, H20)
- Density
- 1.34
- bulk density
- 400kg/m3
- refractive index
- -32 ° (C=1, H2O)
- storage temp.
- 2-8°C
- solubility
- 20% NH3: 0.1 g/mL at 20 °C, clear, colorless
- form
- powder
- pka
- 2.46(at 25℃)
- color
- White to yellow-white
- PH
- 5.5-7.0 (10g/l, H2O, 20℃)
- Odor
- wh. cryst. or cryst. odorless powd., sl. bitter taste
- biological source
- non-animal source
- optical activity
- [α]20/D 31.5±1°, c = 1% in H2O
- Water Solubility
- 11.4 g/L (25 ºC)
- Merck
- 14,9797
- BRN
- 86197
- Stability:
- Stable. Incompatible with strong acids, strong oxidizing agents.
- InChIKey
- QIVBCDIJIAJPQS-VIFPVBQESA-N
- LogP
- 0.704 (est)
- CAS DataBase Reference
- 73-22-3(CAS DataBase Reference)
- NIST Chemistry Reference
- L-Tryptophan(73-22-3)
- EPA Substance Registry System
- L-Tryptophan (73-22-3)
- Absorption
- cut-off at 326nm in 0.5 M HCl at 0.5M
Safety Information
- Symbol(GHS)
GHS05,GHS02
- Signal word
- Danger
- Hazard statements
- H314-H225-H290
- Precautionary statements
- P501-P240-P210-P233-P234-P243-P241-P242-P264-P280-P370+P378-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P406-P405
- Hazard Codes
- Xi
- Risk Statements
- 33-40-62-41-37/38-36/37/38-22
- Safety Statements
- 24/25-36/37/39-36-26
- WGK Germany
- 2
- RTECS
- YN6130000
- F
- 8
- TSCA
- Yes
- HS Code
- 29339990
- Hazardous Substances Data
- 73-22-3(Hazardous Substances Data)
- Toxicity
- LD508mmol / kg (rat, intraperitoneal injection). It is safe when used in food (FDA, §172.320, 2000).
Use
L-tryptophan, an essential aminoacid and precursor of serotonin, was introduced into medicine in 1963 for the treatment of depression and sleep disorders. Its effectiveness in these conditions has, however, never been convincingly demonstrated. It is also widely used in dietary supplements, parenteral nutrition preparations and dietary products for children with phenylketonuria. In 1989, reports from the USA showed an association between the consumption of L-tryptophan containing preparations and the development of eosiniphilia-myalgia syndrome (EMS), a condition characterized by intense eosinophilia, severe muscle and joint pain, swelling of the arms and legs, skin rashes and possible fever. Some of the reported cases have been fatal. Since it is not yet clear whether L-tryptophan itself or an unidentified contaminant is the cause of the EMS, many drug regulatory authorities have suspended the marketing authorization of products containing tryptophan pending further investigation, whereas others have withdrawn these products or restricted their use.
1 supplier list of "L-Tryptophan"
- Product Name:L-Tryptophan
- Company Type: Reagent
- Country/Region: BANGLADESH