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Postion:Product Catalog >Zatolmilast
Zatolmilast
  • Zatolmilast

Zatolmilast NEW

Price $64 $137 $257
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-28

Product Details

Product Name: Zatolmilast CAS No.: 1606974-33-7
Purity: 99.31% Supply Ability: 10g
Release date: 2025/07/28

Product Introduction

Bioactivity

NameZatolmilast
DescriptionZatolmilast (BPN14770) is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).
In vivoBPN14770 increases brain cAMP increases phosphorylation of CREB and increases the production of brain-derived neurotrophic factor (BDNF) in the hippocampus [1]. BPN14770 (0.1-30 mg/kg; p.o.; 24 hours) provides cognitive benefit in the mouse novel object recognition at doses above 0.3 mg/kg [2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 260 mg/mL (640.71 mM), Sonication is recommended.
KeywordsZatolmilast | Phosphodiesterase (PDE) | phosphodiesterase | PDE4D7 | PDE4D3 | Inhibitor | inhibit | BPN-14770 | BPN 14770
Inhibitors RelatedTheophylline monohydrate | Acefylline | Roflumilast | Theobromine | Apremilast | Isoprenaline hydrochloride | Indomethacin | Icariin | Theophylline | Vardenafil hydrochloride | Doxofylline | Sildenafil citrate
Related Compound LibrariesFailed Clinical Trials Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Pediatric Drug Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | NO PAINS Compound Library | Metabolism Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Fluorochemical Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$64.00/1mg
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TargetMol Chemicals Inc.
2025-07-12
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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