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Postion:Product Catalog >Biochemical Engineering>Nucleoside drugs>Deoxynucleotides and their analogs>Zalcitabine
Zalcitabine
  • Zalcitabine

Zalcitabine NEW

Price $30 $43 $61
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-26

Product Details

Product Name: Zalcitabine CAS No.: 7481-89-2
Purity: 99.78% Supply Ability: 10g
Release date: 2025/07/26

Product Introduction

Bioactivity

NameZalcitabine
DescriptionZalcitabine (Dideoxycytidine)(Dideoxycytidine;ddC; 2', 3'-Dideoxycytidine) is a nucleoside analog reverse transcriptase inhibitor (NRTI); At low concentrations, It can potently inhibit HIV replication by binding to reverse transcriptase terminated synthesis of viral DNA chain.
In vitroZalcitabine is a dideoxynucleoside antiretroviral agent that is phosphorylated to the active metabolite 2',3'-dideoxycytidine 5'-triphosphate (ddCTP) in both uninfected and HIV-infected cells. At therapeutic concentrations, ddCTP inhibits HIV replication by targeting reverse transcriptase and terminating the elongation of proviral DNA. Zalcitabine also inhibits the cellular uptake of [3H]-PAH in CHO/hOAT1 cells, with an IC50 value of 1.23 mM, and its uptake increases threefold with enhanced hOAT1 activity in these cells.
Storagestore at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 60 mg/mL (284.06 mM), Sonication is recommended.
KeywordsZalcitabine | ReverseTranscriptase | Reverse Transcriptase | NSC-606170 | NSC606170 | Inhibitor | inhibit | Human immunodeficiency virus | HIVProtease | HIV Protease | HIV
Inhibitors RelatedStavudine | 5-Fluorouracil | Emtricitabine | Valproic acid sodium salt | Dolutegravir intermediate-1 | Dextran sulfate sodium salt (MW 4500-5500) | Lamivudine | Probenecid | Chloroquine phosphate | Valproic Acid | Decanedioic acid | Tenofovir
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | ReFRAME Related Library | Drug Repurposing Compound Library | Anti-Viral Compound Library | Inhibitor Library | NO PAINS Compound Library | FDA-Approved Drug Library | Orally Active Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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