
Win-62005 NEW
Price | $1520 | $1980 | $2500 |
Package | 25mg | 50mg | 100mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-17 |
Product Details
Product Name: Win-62005 | CAS No.: 152633-54-0 |
Supply Ability: 10g | Release date: 2025/07/17 |
Product Introduction
Bioactivity
Name | Win-62005 |
Description | Win-62005 is an inhibitor of cyclic AMP phosphodiesterase III (PDE III)(Kis: 25 and 26 nM for rat heart and canine aorta). |
In vitro | Win-62005 is a competitive inhibitor of cyclic GMP-inhibitable low Km cyclic AMP phosphodiesterase (PDE III) found in rat heart and canine aorta, demonstrating high affinity with inhibition constants (Ki) of approximately 25±3 nM and 26±5 nM, respectively. Furthermore, it exhibits significant selectivity, being at least 160-fold more selective for PDE III over other phosphodiesterase (PDE) isozymes. |
In vivo | Win-62005(p.o. administration of 1 mg/kg) LVdP/dtmax is significantly increased in 30 min and remains increased for at least 6 h. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Keywords | Win-62005 | Win62005 | Win 62005 | PDE III |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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