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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antifungal Drugs>Voriconazole
Voriconazole
  • Voriconazole

Voriconazole NEW

Price $30 $50 $71
Package 10mg 25mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-04-27

Product Details

Product Name: Voriconazole CAS No.: 137234-62-9
Purity: 99.91% Supply Ability: 10g
Release date: 2025/04/27

Product Introduction

Bioactivity

NameVoriconazole
DescriptionVoriconazole (UK-109496) is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 [CYP3A].
In vitroIntraperitoneal administration of 5 mg/kg Voriconazole combined with 1.25 mg/kg Amphotericin B significantly reduces fungal counts in selected tissues of guinea pigs when compared to control groups. Furthermore, Voriconazole at 5 mg/kg, when combined with any dose of Caspofungin Acetate, decreases tissue fungal loads, specifically demonstrating a significant reduction in the number of positive cultures. In immunocompromised guinea pigs with pulmonary aspergillosis, Voriconazole effectively reduces pulmonary Aspergillus spp. counts, displaying superior results to those observed with Itraconazole.
In vivoIn vitro, Voriconazole exhibits greater or comparable antifungal activity against most tested molds than Itraconazole and Amphotericin B. Voriconazole effectively inhibits certain conditioned filamentous fungi and dimorphic fungi (molds), as well as yeast species. At concentrations of ≤1 μg/mL, Voriconazole can inhibit 95% of fungal strains.
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : < 1 mg/mL (insoluble or slightly soluble)
Ethanol : 16 mg/mL (45.8 mM), Sonication is recommended.
DMSO : 50 mg/mL (143.14 mM), Sonication is recommended.
KeywordsVoriconazole | UK109496 | UK 109496 | triazole | pulmonary | murine | Inhibitor | inhibit | Fungal | broad-spectrum | blastomycosis | antifungal | 14-α Demethylase
Inhibitors RelatedDehydroacetic acid sodium | Chlorobutanol hemihydrate | 2-Butyl-1,2-benzisothiazolin-3-one | Tebuconazole | Potassium gluconate | Chitosan (MW 150000) | Methyl 2-amino-5-bromobenzoate | Metronidazole | Paclobutrazol | L-Lysine | Lauryl betaine | Geraniol
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | ReFRAME Related Library | EMA Approved Drug Library | Anti-Fungal Compound Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Human Metabolite Library

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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