Vitamin K1-d7

Modify Date: 2024-01-02 13:56:58

Vitamin K1-d7 structure	Common Name	Vitamin K1-d7
	CAS Number	1233937-39-7	Molecular Weight	457.73900
	Density	0.999 g/mL at 25°C	Boiling Point	N/A
	Molecular Formula	C31H39D7O2	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Purity		Quantity		Budget		Inquiry

Use of Vitamin K1-d7 Vitamin K1 D7 (Phylloquinone D7) is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1][2].

• Properties

• Spectrum

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 Names

Name	Vitamin K1-d7
Synonym	More Synonyms

 Vitamin K1-d7 Biological Activity

Description	Vitamin K1 D7 (Phylloquinone D7) is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Basset GJ, et al. Phylloquinone (Vitamin K1): Occurrence, Biosynthesis and Functions. Mini Rev Med Chem. 2016 Jun 22. [3]. Orlando A, et al. Vitamin K1 exerts antiproliferative effects and induces apoptosis in three differently graded human colon cancer cell lines. Biomed Res Int. 2015;2015:296721. [4]. Ibarrola-Jurado N, et al. Dietary phylloquinone intake and risk of type 2 diabetes in elderly subjects at high risk of cardiovascular disease. Am J Clin Nutr. 2012 Nov;96(5):1113-8. [5]. Kim M, et al. Vitamin K1 (phylloquinone) and K2 (menaquinone-4) supplementation improves bone formation in a high-fat diet-induced obese mice. J Clin Biochem Nutr. 2013 Sep;53(2):108-13. [6]. Hemmati AA, et al. Topical vitamin K1 promotes repair of full thickness wound in rat. Indian J Pharmacol. 2014 Jul-Aug;46(4):409-12.

 Chemical & Physical Properties

Density	0.999 g/mL at 25°C
Molecular Formula	C31H39D7O2
Molecular Weight	457.73900
Exact Mass	457.39400
PSA	34.14000
LogP	9.15760

 Safety Information

RIDADR	NONH for all modes of transport

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