Product Name:    Vilazodone Hydrochloride

Synonyms:    5-[4-[4-(5-Cyanoindol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide hydrochloride;Vilazodone hydrochloride;5-[4-[4-(5-Cyanoindol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxaMide hydrochloride、Vilazodone hydrochloride;EMD 68843;SB 659746A;CS-796;5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamide hydrochloride;VILAZODONE; EMD 68843; SB 659746A

CAS:    163521-08-2

MF:    C26H28ClN5O2

MW:    477.98582

EINECS:    695-883-8

Product Categories:    API;Inhibitors

form     powder

color     white to beige

Vilazodone is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A (IC50s = 0.2 and 0.5 nM, respectively). It increases extracellular 5-HT in the rat ventral hippocampus and frontal cortex when administered intraperitoneally at doses of 1 and 3 mg/kg. Vilazodone (1 mg/kg, i.p.) decreases immobility in the forced swim test in both rats and mice. Formulations containing vilazodone have been used in the treatment of depression.