
VEGFR2 Kinase Inhibitor II NEW
Price | Get Latest Price |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-18 |
Product Details
Product Name: VEGFR2 Kinase Inhibitor II | CAS No.: 288144-20-7 |
Supply Ability: 10g | Release date: 2025/07/18 |
Product Introduction
Bioactivity
Name | VEGFR2 Kinase Inhibitor II |
Description | Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor II is a reversible, cell-permeable inhibitor of VEGFR2's kinase activity (IC50 = 70 nM). It less potently inhibits the platelet-derived growth factor receptor β (PDGFRβ; IC50 = 920 nM) and related receptor and non-receptor tyrosine kinases. VEGFR2 kinase inhibitor II blocks the growth of human umbilical vein endothelial cells stimulated with either VEGF or PDGF (IC50s = 110 nM and 2 μM, respectively). |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMF : 20 mg/mL (58.27 mM), Sonication is recommended. DMSO : 10 mg/mL (29.14 mM), Sonication is recommended. |
Keywords | VEGFR2 Kinase Inhibitor II | VEGFR-2 Kinase Inhibitor II |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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