
Ursolic acid NEW
Price | $46 |
Package | 1mL |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-04-30 |
Product Details
Product Name: Ursolic acid | CAS No.: 77-52-1 |
Purity: 99.79% | Supply Ability: 10g |
Release date: 2025/04/30 |
Product Introduction
Bioactivity
Name | Ursolic acid |
Description | Ursolic acid (Prunol) is a natural product, a pentacyclic triterpene carboxylic acid extracted from Rhododendron caprifolium. Ursolic acid has anti-tumor, anti-inflammatory, anti-bacterial and hypoglycemic activities. |
In vitro | METHODS: Embryonal carcinoma cells NTERA-2 and NCCIT were treated with Ursolic acid (1-50 μM) for 24 h. Cell viability was measured by MTT assay. RESULTS: Concentration-dependent inhibition of NTERA-2 and NCCIT cell viability by Ursolic acid treatment. [1] METHODS: Lung cancer cells H460 and H1975 were treated with Ursolic acid (5-20 nM) for 48 h. Apoptosis was detected by Flow cytometry. RESULTS: Ursolic acid significantly increased the percentage of Annexin V (+) apoptotic cells compared to control. [2] |
In vivo | METHODS: To investigate the antidepressant-like effects, Ursolic acid (0.001-10 mg/kg, distilled water with 10% Tween 80) was orally administered to Swiss mice, and the TST, FST, or open-field test was performed 60 min later. RESULTS: Ursolic acid shortened the immobilization time in TST and FST.The antidepressant-like effect of Ursolic acid in TST may be mediated by the activation of dopamine D1 and D2 receptors interacting with the dopaminergic system. [3] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O : < 1 mg/mL (insoluble or slightly soluble) Propylene glycol : 4.76 mg/mL (10.42 mM), Sonification is recommended. DMSO : 50 mg/mL (109.48 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) |
Keywords | Ursolic acid | NSC4060 | NSC-167406 | NSC167406 | NSC 4060 | Inhibitor | inhibit | EndogenousMetabolite | Endogenous Metabolite | Autophagy |
Inhibitors Related | Sucrose | Hydroxychloroquine | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Formamide | Paeonol | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
Related Compound Libraries | Anti-Tumor Natural Product Library | Failed Clinical Trials Compound Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Anti-Cancer Clinical Compound Library | Natural Product Library | Tobacco Monomer Library | Antiparasitic Natural Product Library | Immunology/Inflammation Compound Library | Cosmetic Ingredient Compound Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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