Urethane NEW
| Price | $29 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-30 |
Product Details
| Product Name: Urethane | CAS No.: 51-79-6 |
| Purity: 99.63% | Supply Ability: 10g |
| Release date: 2025/04/30 |
Product Introduction
Bioactivity
| Name | Urethane |
| Description | Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes. |
| In vitro | urethane has a spectrum of action on ion channels, which is distinct from other anesthetics. It significantly potentiates the current responses of both GABAA and glycine receptors in a reversible and concentration-dependent manner. Conversely, urethane (10–300 mM) inhibits the responses of NMDA and AMPA receptors. Also, urethane potentiates the function of an nACh receptor and neuronal nicotinic acetylcholine, γ-aminobutyric acid A, and glycine receptors[3]. |
| In vivo | Urethane, a carcinogenic substance, is favored for acute in vivo electrophysiological experiments because it induces long-lasting steady level of anesthesia with muscle relaxation and minimally affects the autonomic and cardiovascular systems[2]. Urethane affects both inhibitory and excitatory systems but the magnitude of the alterations is less than that produced by other more selective anesthetics[3]. But also, Urethane anesthesia is usually restricted to terminal (acute) experiments due to its potential long-term toxicity[1]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 55 mg/mL (617.35 mM), Sonication is recommended. |
| Keywords | α4β2 nAChR | Urethane | Pesticide | Parasite | NMDA receptor | narcosis | mutagen | Inhibitor | inhibit | Glycine receptor | GABAReceptor | GABAR | GABA Receptor | clastogen | Chloridechannel | Chloride channel | carbamic | Bacterial | AMPA | acid |
| Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Kojic acid | Methyl anthranilate | Kanamycin sulfate | p-Hydroxybenzaldehyde | Sulfamethoxazole sodium | Hydroxychloroquine | Doxycycline | Isoeugenol | Dimethyl sulfoxide |
| Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Natural Product Library | Drug Repurposing Compound Library | Antiparasitic Natural Product Library | Tobacco Monomer Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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