TRIM NEW
| Price | $47 | $68 | $165 |
| Package | 50mg | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-30 |
Product Details
| Product Name: TRIM | CAS No.: 25371-96-4 |
| Purity: 98.98% | Supply Ability: 10g |
| Release date: 2025/04/30 |
Product Introduction
Bioactivity
| Name | TRIM |
| Description | TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS. |
| In vivo | TRIM is a poor inhibitor of bovine aortic endothelial NOS with an IC50 of 1057.5 microM. TRIM (10-50 mg kg-1) administered i.p. exhibits dose-related antinociceptive activity in the mouse (assessed as inhibition of late phase formalin-induced hindpaw licking behaviour) with an ED50 of 85.8 mumol kg-1. In contrast, TRIM (50 mg kg-1, i.p.) failed to influence mean arterial blood pressure in the urethane-anaesthetized mouse[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 2.12 mg/mL (9.99 mM), Sonication is recommended. |
| Keywords | TRIM | NOS | NO Synthase | nNOS | Nitric oxide synthases | iNOS | Inhibitor | inhibit | eNOS | anxiolytic-like effects | antidepressant |
| Inhibitors Related | Miconazole | Aminoguanidine hydrochloride | L-NAME hydrochloride | EIT hydrobromide | 3-Bromo-7-nitroindazole | Dexamethasone acetate | S-Methylisothiourea sulfate | Cannabigerol | 1400W dihydrochloride | Flavone | S-(2-aminoethyl) Isothiourea (dihydrobromide) | Diallyl disulfide |
| Related Compound Libraries | Bioactive Compound Library | Antidepressant Compound Library | Inhibitor Library | Neuroprotective Compound Library | NO PAINS Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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