TRIM24/BRPF1-IN-2 NEW
| Price | $335 | $970 | Get Latest Price |
| Package | 1mg | 5mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-16 |
Product Details
| Product Name: TRIM24/BRPF1-IN-2 | CAS No.: 3033288-68-2 |
| Purity: 99.13% | Supply Ability: 10g |
| Release date: 2025/05/16 |
Product Introduction
Bioactivity
| Name | TRIM24/BRPF1-IN-2 |
| Description | TRIM24/BRPF1-IN-2 is a selective dual TRIM24/BRPF1 inhibitor with anticancer activity that inhibits proliferation, gene and protein expression, and colony formation of prostate cancer cells in a dose-dependent manner. |
| In vitro | TRIM24/BRPF1-IN-2 significantly inhibited the growth of prostate cell lines (C4-2B, LNCaP, and 22Rv1) after treatment at concentrations of 0-10 μM for 48 h. The IC50 values were 0.78 μM, 1.07 μM, and 0.82 μM, respectively.TRIM24/BRPF1-IN-2 was also able to inhibit prostate cancer cells' gene and protein expression. In addition, TRIM24/BRPF1-IN-2 showed good Caco-2 permeability. [1] |
| In vivo | TRIM24/BRPF1-IN-2 administered once daily by intraperitoneal injection for 21 consecutive days at a dose of 50 mg/kg significantly inhibited tumor growth (TGI = 53%) and no significant toxicity was observed. [1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | EpigeneticReaderDomain | Epigenetic Reader Domain | BRPF1 |
| Inhibitors Related | ABBV-744 | CeMMEC1 | 3-methyl-1,2,3,4-tetrahydroquinazolin-2-one | (+)-JQ-1 | J-147 | Anacardic Acid | Curcumin | dBET6 | Piflufolastat | Naphthol AS-E | Bisdemethoxycurcumin | GSK1379725A |
| Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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