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Postion:Product Catalog >TRIM24/BRPF1-IN-2
TRIM24/BRPF1-IN-2
  • TRIM24/BRPF1-IN-2

TRIM24/BRPF1-IN-2 NEW

Price $335 $970 Get Latest Price
Package 1mg 5mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-05-16

Product Details

Product Name: TRIM24/BRPF1-IN-2 CAS No.: 3033288-68-2
Purity: 99.13% Supply Ability: 10g
Release date: 2025/05/16

Product Introduction

Bioactivity

NameTRIM24/BRPF1-IN-2
DescriptionTRIM24/BRPF1-IN-2 is a selective dual TRIM24/BRPF1 inhibitor with anticancer activity that inhibits proliferation, gene and protein expression, and colony formation of prostate cancer cells in a dose-dependent manner.
In vitroTRIM24/BRPF1-IN-2 significantly inhibited the growth of prostate cell lines (C4-2B, LNCaP, and 22Rv1) after treatment at concentrations of 0-10 μM for 48 h. The IC50 values were 0.78 μM, 1.07 μM, and 0.82 μM, respectively.TRIM24/BRPF1-IN-2 was also able to inhibit prostate cancer cells' gene and protein expression. In addition, TRIM24/BRPF1-IN-2 showed good Caco-2 permeability. [1]
In vivoTRIM24/BRPF1-IN-2 administered once daily by intraperitoneal injection for 21 consecutive days at a dose of 50 mg/kg significantly inhibited tumor growth (TGI = 53%) and no significant toxicity was observed. [1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
KeywordsEpigeneticReaderDomain | Epigenetic Reader Domain | BRPF1
Inhibitors RelatedABBV-744 | CeMMEC1 | 3-methyl-1,2,3,4-tetrahydroquinazolin-2-one | (+)-JQ-1 | J-147 | Anacardic Acid | Curcumin | dBET6 | Piflufolastat | Naphthol AS-E | Bisdemethoxycurcumin | GSK1379725A
Related Compound LibrariesBioactive Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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