TM-N1324 NEW
| Price | $97 | $189 | $413 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-21 |
Product Details
| Product Name: TM-N1324 | CAS No.: 1144477-35-9 |
| Purity: 90.39% | Supply Ability: 10g |
| Release date: 2025/05/21 |
Product Introduction
Bioactivity
| Name | TM-N1324 |
| Description | TM-N1324 is a GPR39 agonist. TM-N1324 activates human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively. TM-N1324 has similar potencies to murine GPR39 with EC50s of 180 nM and 5 nM, respectively. |
| In vitro | Measurements of somatostatin confirms that the GPR39 agonist TM-N1324 increases somatostatin release by 53%. TM-N1324 is found to have promising in vitro ADME properties. TM-N1324 has reasonably good aqueous solubility (65 μM at pH 7.0)[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 10 mg/mL (25.14 mM), Sonication and heating are recommended. |
| Keywords | TM-N-1324 | TM-N1324 | TMN1324 | TM-N 1324 | TM N1324 | murine GPR39 without Zn2+ | murine GPR39 with Zn2+ | Inhibitor | inhibit | human GPR39 without Zn2+ | human GPR39 with Zn2+ | Growth hormone secretagogue receptor | GPR39 | GHSR |
| Inhibitors Related | Ibutamoren Mesylate | Capromorelin Tartrate | AnaMorelin hydrochloride | YIL 781 | Anamorelin | CJC-1295 acetate(863288-34-0 free base) | hGPR91 antagonist 1 | L-692429 | TC-G-1008 | NF-56-EJ40 hydrochloride | Human growth hormone-releasing factor acetate | Cortistatin-8 acetate |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Endocrinology-Hormone Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | GPCR Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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