Product Details
Product Name:
TL13-22 |
CAS No.:
2229036-65-9 |
Purity:
99.13% |
Supply Ability:
10g |
Release date:
2025/07/07 |
Product Introduction
Bioactivity
Name | TL13-22 |
Description | TL13-22 is a potent inhibitor of Anaplastic Lymphoma Kinase (ALK) with an IC?? value of 0.54 nM and does not lead to degradation of ALK proteins.TL13-22 is often used as a negative control for TL13-12 (induces ALK protein degradation) as a negative control.TL13-22 also induces degradation of other kinases, including Aurora A, FER, PTK2, and RPS6KA1. |
In vitro | TL13-22 prompted the concentrations of Aurora A, FER, PTK2 and RPS6KA1 kinase reduction at 11.3, 5.74, 18.4 and 65.9 nM, respectively. [1] |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 200 mg/mL (211.08 mM), Sonication is recommended.
|
Keywords | TL13-22 | TL-13-22 | TL1322 | TL13 22 |
Inhibitors Related | Lorlatinib | Entrectinib | Alectinib hydrochloride | Alectinib | SB-431542 | RepSox | Crizotinib | Vactosertib | Ceritinib | Brigatinib | A 83-01 | K02288 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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