Tipepidine NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-01 |
Product Details
| Product Name: Tipepidine | CAS No.: 5169-78-8 |
| Supply Ability: 10g | Release date: 2025/05/01 |
Product Introduction
Bioactivity
| Name | Tipepidine |
| Description | Tipepidine is a non-narcotic antitussive with an antidepressant-like effect. Tipepidine reversibly inhibits dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK) ) (IC 50 = 7.0 μM) and subsequently activates VTA dopamine neurons. |
| In vivo | Tipepidine administered intraperitoneally (i.p.) at doses ranging from 10 to 40 mg/kg for durations between 0.5 and 23 hours notably reduced immobility time in the forced swimming test among ACTH-treated male Wistar rats, weighing 150-240 g and aged 5-7 weeks. At a specific dosage of 40 mg/kg, tipepidine elevated the extracellular dopamine levels in the nucleus accumbens (NAc) in these rats. The study utilized dosages of 10, 20, and 40 mg/kg, with administration times at 0.5, 5, and 23 hours, leading to the observed decrease in immobility time in the forced swimming test for ACTH-treated subjects. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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