Product Details
| Product Name:
Terevalefim |
CAS No.:
1070881-42-3 |
| Purity:
99.80% |
Supply Ability:
10g |
| Release date:
2025/07/26 |
Product Introduction
Bioactivity
| Name | Terevalefim |
| Description | Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor. |
| In vitro | Terevalefim (ANG-3777) (0-10 μM) significantly inhibited cancer cell proliferation in HUVECs[2]. |
| In vivo | Terevalefim (ANG-3777) reduces apoptosis, enhances proliferation, and supports organ repair and function in animal models[1]. Additionally, Terevalefim (ANG-3777, 40 mg/kg, IP) induces phosphorylation of the c-Met receptor in rats[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 100 mg/mL (567.41 mM), Sonication is recommended.
|
| Keywords | transplantation | Terevalefim | kidney | injury | Inhibitor | inhibit | HGFR | HGF | c-Met/HGFR | cMet/HGFR | c-Met | cMet | ANG-3777 | ANG3777 | ANG 3777 | AKI | acute |
| Inhibitors Related | Capmatinib 2HCl | (±)-Norcantharidin | L-Ascorbic acid 2-phosphate trisodium | Crizotinib | Amuvatinib | Norcantharidin | AMG-458 | Cabozantinib S-malate | Capmatinib xHCl | Bacitracin Zinc | Capmatinib | BMS 777607 |
| Related Compound Libraries | Anti-Colorectal Cancer Compound Library | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Tyrosine Kinase Inhibitor Library | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Bioactive Compounds Library Max | Anti-Liver Cancer Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States