Tannic acid NEW
| Price | $41 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-30 |
Product Details
| Product Name: Tannic acid | CAS No.: 1401-55-4 |
| Supply Ability: 10g | Release date: 2025/04/30 |
Product Introduction
Bioactivity
| Name | Tannic acid |
| Description | Tannic acid (Gallotannic acid) is a novel hERG channel blocker. |
| In vitro | METHODS: Rat cardiomyocytes H9C2 were treated with Tannic acid (5-50 μM) for 24 h. Cell viability was determined by CCK-8 Assay. RESULTS: Treatment of H9C2 cells with Tannic acid concentration ≥ 30 μM resulted in a significant decrease in cell viability. [1] METHODS: Human lung cancer cells A549 were treated with Tannic acid (20-60 μM) for 24-48 h. Cell cycle was measured by Flow cytometry. RESULTS: Tannic acid inhibited cell viability in a dose-dependent manner at 24 h, with higher inhibition after 48 h. The IC50 values for Tannic acid were estimated to be in the range of 40-60 μM at 24 h and 20-40 μM at 48 h. [1] METHODS: Human lung cancer cells A549 were treated with Tannic acid (20-60 μM) for 24-48 h. Cell cycle was measured by Flow cytometry. [2] |
| In vivo | METHODS: To investigate the effects on oxidative stress mice, Tannic acid (2.5-10 mg/kg) was administered orally to diquat-induced oxidative stress C57BL/6J mouse model once daily for ten days. RESULTS: Tannic acid pretreatment in the oxidative stress mouse model failed to alter antioxidant enzymes but modulated jejunal morphology, colon length, antioxidant pathways, and intestinal barrier in the diquat oxidative model. [3] |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 25 mg/mL (14.7 mM), Sonication is recommended. H2O : 17.24 mg/mL (10.13 mM), Sonication is recommended. |
| Keywords | Tannic acid | PotassiumChannel | Potassium Channel | hERG | CXCR |
| Inhibitors Related | Minoxidil sulfate | Hydrochlorothiazide | (±)-Naringenin | Tetraethylammonium bromide | Halothane | Ursodeoxycholic acid | Neratinib | Cloperastine hydrochloride | Nifedipine | 2,2,2-Trichloroethanol | Indapamide | Nicotinamide N-oxide |
| Related Compound Libraries | Polyphenolic Natural Product Library | Traditional Chinese Medicine Monomer Library | Anti-COVID-19 Traditional Chinese Medicine Compound Library | Toxic Compound Library | Chinese Pharmacopoeia Natural Product Library | Cosmetic Ingredient Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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