T-1095 NEW
| Price | $48 | $97 | $139 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-19 |
Product Details
| Product Name: T-1095 | CAS No.: 209746-59-8 |
| Purity: 99.56% | Supply Ability: 10g |
| Release date: 2025/07/19 |
Product Introduction
Bioactivity
| Name | T-1095 |
| Description | T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2). |
| In vivo | Administration of 0.03% and 0.1% (wt/wt diet) T-1095 to STZ rats for 4 weeks improved the hyperglycemia and dose-dependently decreased HbA1c[1]. Moreover, treatment with 0.1% (wt/wt diet) T-1095 in STZ rats for 8 weeks not only reduced blood glucose and HbA1c, levels but also prevented the elevation of urinary albumin levels and kidney weight and the development of epithelial vacuolation[1]. The expression of renal SGLT2, a major glucose transporter in the kidney, was not different in normal, STZ, and T-1095-treated STZ rats. In contrast, the elevated renal GLUT2 level in STZ rats was suppressed by T-1095[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 60 mg/mL (116.17 mM), Sonication is recommended. |
| Keywords | T-1095 | T1095 | T 1095 | Sodium-dependent glucose cotransporters | SGLT2 | SGLT1 | SGLT | orally active | Inhibitor | inhibit | GLUT2 | antidiabetic |
| Inhibitors Related | Dapagliflozin ((2S)-1,2-propanediol, hydrate) | MSNBA | LDN-212320 | Ipragliflozin | Canagliflozin hemihydrate | SLC26A3-IN-1 | Phlorizin | BAY-876 | Phloretin | Empagliflozin | Canagliflozin | Ertugliflozin |
| Related Compound Libraries | Glycolysis Compound Library | Glycometabolism Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Anti-Diabetic Compound Library | Glutamine Metabolism Compound Library | Anti-Obesity Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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