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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Sulfonamides and synergist>Sulfaguanidine
Sulfaguanidine
  • Sulfaguanidine

Sulfaguanidine NEW

Price $78
Package 5g
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-30

Product Details

Product Name: Sulfaguanidine CAS No.: 57-67-0
Purity: 97.78% Supply Ability: 10g
Release date: 2025/07/30

Product Introduction

Bioactivity

NameSulfaguanidine
DescriptionSulfaguanidine (Guanicil), a sulfonamide, is served as an anti-infective agent.
In vitroAdult rats exhibit a more robust elimination capability for Sulfaguanidine when compared to neonatal rats. Pharmacokinetic studies of gastrointestinal absorption reveal that, following oral administration, the peak plasma concentration in adult rats is significantly lower than that in neonatal rats, although there is no marked difference in the time taken to reach peak blood levels. The absolute bioavailability in adult rats (12.76%) is approximately one-fifth that of neonatal rats (57.86%). In adults, the plasma elimination of Sulfaguanidine, administered intravenously at doses of 2.5 or 25 mg/kg, can be described by a two-compartment open model. Conversely, the plasma concentration profile of Sulfaguanidine, post oral administration of 25 mg/kg, is consistent with a one- or two-compartment open model. Consequently, Sulfaguanidine is less readily absorbed in adult rats, while neonatal rats demonstrate effective absorption.
In vivoSulfaguanidine, one of the earliest sulfa drugs employed in the treatment of intestinal infections, effectively inhibits the synthesis of nutritional factors in intestinal bacteria. It also efficiently impedes the growth of Gram-negative enterobacteria.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationEthanol : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 55 mg/mL (256.72 mM), Sonication is recommended.
Keywordssulfonamide | Sulfaguanidine | Inhibitor | inhibit | infections | enteric | dysentery | DHPS | Bacterial | bacillary | antimicrobial,antibiotic | Antibiotic
Inhibitors RelatedNeomycin sulfate | Stavudine | Ampicillin sodium | Kanamycin sulfate | Sodium 4-phenylbutyrate | Sulfamethoxazole sodium | Hydroxychloroquine | Guanidine hydrochloride | Doxycycline | Paeonol | Naringin | Dimethyl sulfoxide
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | Autophagy Compound Library | Drug Repurposing Compound Library | Drug-Fragment Library | Anti-Cancer Approved Drug Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library | Human Metabolite Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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