
Suberoyl bis-hydroxamic acid NEW
Price | $29 |
Package | 100mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-17 |
Product Details
Product Name: Suberoyl bis-hydroxamic acid | CAS No.: 38937-66-5 |
Supply Ability: 10g | Release date: 2025/07/17 |
Product Introduction
Bioactivity
Name | Suberoyl bis-hydroxamic acid |
Description | Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on the N-terminal of the core histones. |
In vitro | In MEL cells, SBHA leads to the accumulation of acetylated H4, indicating the hydroxamic acid groups are involved in increasing potency and inhibition of HDAC activity. In Jurkat cells, SHBA inhibits the HDAC1 and HDAC3 activities with IC50 value of 0.25 and 0.3 μm respectively. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | H2O : 8.16 mg/mL (40 mM), Sonication is recommended. DMSO : 49 mg/mL (239.93 mM), Sonication is recommended. |
Keywords | thyroid | Suberoyl bis-hydroxamic acid | Suberoyl bishydroxamic acid | Suberoyl bis hydroxamic acid | neuroendocrine malignancy | neoplastic disease | neoplasia | MTC | mesothelioma | Medullary | Malignant | Inhibitor | inhibit | Histone deacetylases | HDAC3 | HDAC1 | HDAC | carcinoma | Apoptosis |
Inhibitors Related | Stavudine | 5-Fluorouracil | Cysteamine hydrochloride | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Tributyrin | Valproic Acid | Curcumin | L-Ascorbic acid sodium salt | Alginic acid |
Related Compound Libraries | Reprogramming Compound Library | DNA Damage & Repair Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Anti-Breast Cancer Compound Library | Hematonosis Compound Library | Chromatin Modification Compound Library | Inhibitor Library | Mitochondria-Targeted Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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