Product Details
| Product Name:
SMBA1 |
CAS No.:
906440-37-7 |
| Purity:
99.2% |
Supply Ability:
10g |
| Release date:
2025/07/23 |
Product Introduction
Bioactivity
| Name | SMBA1 |
| Description | SMBA1 is a highly potent Bax agonist with antitumor activity that induces cell cycle arrest and apoptosis in malignant glioma cells. SMBA1 can be used to study triple-negative breast cancer. |
| In vitro | SMBA1 exhibited Bax agonist activity by inhibiting the phosphorylation of S184, promoting the insertion of Bax into the mitochondrial membrane and the formation of Bax oligomers, and thereby inducing conformational changes in Bax. SMBA1 (0, 0.1, 1, 5, 10 μM; 24 hr) potentiated Bax expression in a dose-dependent manner in A549 cells. [1] |
| In vivo | SMBA1 (2, 10, 40, 60 mg/kg; intraperitoneal injection; once daily for 10 days) exhibited antitumor activity in mice. [1] |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | SMBA-1 | SMBA1 | SMBA 1 | Bax |
| Inhibitors Related | Gossypol (acetic acid) | (S)-(+)-Ibuprofen | Allethrin | Erianin | Navitoclax | Gossypol | Triacetylresveratrol | Diphenyl disulfide | Lisaftoclax | Venetoclax | Sonrotoclax TFA | Thymoquinone |
| Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States