SM1-71 NEW
| Price | $44 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-18 |
Product Details
| Product Name: SM1-71 | CAS No.: 2088179-99-9 |
| Purity: 96% | Supply Ability: 10g |
| Release date: 2025/07/18 |
Product Introduction
Bioactivity
| Name | SM1-71 |
| Description | SM1-71 is a potent multi-targeted acrylamide-modified TAK1 inhibitor that inhibits MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2.SM1-71 can be used as a kinase probe with anticancer activity and inhibits the proliferation of various cancer cell lines. |
| In vitro | Potently inhibiting the proliferation of H23 and Calu-6 non-small cell lung cancer cell lines in a concentration-dependent manner, SM1-71 (0.001-100 μM; 72 h) demonstrates its efficacy. Additionally, SM1-71 induces potent cytotoxicity within 72 hours, with nanomolar values for GR50 and negative GRmax values observed in eight of 11 cancer cell lines[1][2]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 100 mg/mL (215.54 mM), Sonication is recommended. |
| Keywords | threoninkinase | threonin kinase | TGF-β/Smad | TGFβ | TGFbeta/Smad | TGF-beta | TGFbeta | TGF-b/Smad | TGFb | TAK1 | Smad | SM-1-71 | SM171 | SM1 71 | Serinekinase | Serine/threonin kinase | Serine kinase | MAP3K | LIMKinase | LIMK1 | LIM Kinase | bone morphogenetic protein (BMP) | AP2associatedkinase1 | AP2 associated kinase 1 | AAK1(AP2associatedkinase1) | AAK1 (AP2 associated kinase 1) | AAK1 |
| Inhibitors Related | Monocrotaline | Nafamostat mesylate | Hydrochlorothiazide | sodium lauroyl-α-hydroxyethyl sulfonate | Chromenone 1 | Camostat mesylate | Pirfenidone | A 83-01 | Galunisertib | FOY 251 | Alantolactone | Benzamidine hydrochloride |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Kinase Inhibitor Library | Anti-Ovarian Cancer Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Covalent Inhibitor Library | Anti-Cancer Compound Library | TGF-beta/Smad Compound Library | Neuronal Differentiation Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1980.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2025-07-22 | |
| $0.00/5mg |
VIP1Y
|
Guangzhou Tosun Pharmaceutical Ltd
|
2025-02-26 | |
| $0.00/25KG |
VIP6Y
|
Hebei Mujin Biotechnology Co.,Ltd
|
2023-06-27 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY