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Postion:Product Catalog >Sinefungin
Sinefungin
  • Sinefungin

Sinefungin NEW

Price $222 $313
Package 1mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-05-09

Product Details

Product Name: Sinefungin CAS No.: 58944-73-3
Purity: 98.12% Supply Ability: 10g
Release date: 2025/05/09

Product Introduction

Bioactivity

NameSinefungin
DescriptionSinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7/9 inhibitor and ameliorates renal fibrosis by inhibiting H3K4 methylation.
In vitroSinefungin (0.5 or 1.0 μg/mL, 60 minutes) mitigates TGF-β1-induced α-SMA increase and inhibits histone H3K4 monomethylation upregulation in renal epithelial and fibroblast cells [2].
In vivoIn obstructive nephropathy, Sinefungin (10 mg/kg, per day immediately after UUO) improves renal fibrosis [2].
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : 95 mg/mL (249.09 mM), Sonication is recommended.
Keywordsα-SMA | UUP | Sinefungin | SET7/9 | Inhibitor | inhibit | HistoneMethyltransferase | Histone Methyltransferase | H3K4 | Fungal | FSP-1 | collagen 3 | collagen 1 | Antibiotic | A9145 | A 9145
Inhibitors RelatedNeomycin sulfate | Dehydroacetic acid sodium | Potassium gluconate | Ampicillin sodium | Doxycycline (hyclate) | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Penicillin G potassium | Geraniol | EDTA copper(II) disodium salt
Related Compound LibrariesHistone Modification Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Epigenetics Compound Library | Anti-Breast Cancer Compound Library | Antibiotics Library | Inhibitor Library | Microbial Natural Product Library | Anti-Fibrosis Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library | Human Metabolite Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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