SCH 42495 racemate NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-28 |
Product Details
| Product Name: SCH 42495 racemate | CAS No.: 145841-10-7 |
| Supply Ability: 10g | Release date: 2025/07/28 |
Product Introduction
Bioactivity
| Name | SCH 42495 racemate |
| Description | SCH 42495 racemate is the racemate of SCH 42495, an orally active neutral inhibitor of metalloendopeptidase (NEP) with antihypertensive effects. |
| In vitro | in vitro,SCH 42495 selectively inhibits hydrolysis of leu-enkephalin and ANF with IC50 of 8.3 and 10.0 nM, respectively[1]. |
| In vivo | Significant reduction in the pulmonary vascular remodelling and ventricular hypertrophy in hypoxic rats after 10 days caused by SCH 42495 (30 mg/kg; oral gavage; twice daily). Treatment with SCH 42495 (30 mg/kg; oral gavage; twice daily) leads to a decrease in cardiovascular remodelling secondary to chronic hypoxia in rats[2]. SCH 42495 (oral doses of 1, 3, or 10 mg/kg) produces significant reductions in blood pressure in DOCA-N a hypertensive rats of 22±6, 43±7, and 62±12 mm Hg, respectively[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | SCH-42495 | SCH42495 | SCH 42495 racemate | SCH 42495 | racemate | NEP |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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