SCH-23390 hydrochloride NEW
| Price | $33 | $46 | $71 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-19 |
Product Details
| Product Name: SCH-23390 hydrochloride | CAS No.: 125941-87-9 |
| Purity: 99.83% | Supply Ability: 10g |
| Release date: 2025/07/19 |
Product Introduction
Bioactivity
| Name | SCH-23390 hydrochloride |
| Description | SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, with high affinity for the D1 (Ki=0.2 nM) and D5 (Ki=0.3 nM) receptors. |
| Animal Research | Rats are injected with SCH 23390(0, 1, or 10 μg/kg i.p.). |
| In vitro | SCH23390 blocks endogenous GIRK currents induced by either somatostatin or D3 dopamine receptors in AtT-20 cells (IC50=268 nM).SCH 23390 also shows high affinity (Ki=9.3 nM) at h5-HT2C sites. |
| In vivo | In the rat, the repeated administration of SCH 23390 (0.05 mg/kg s.c., thrice daily for 21 days) enhances the steady-state density of dopamine D1 receptors in the striatum (+30%) and substantia nigra (+24%). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 25 mg/mL (77.10 mM), Sonication is recommended. DMSO : 50 mg/mL (154.21 mM), Sonication is recommended. |
| Keywords | SCH-23390 Hydrochloride | R-SCH-23390 Hydrochloride | R-SCH23390 Hydrochloride | R-SCH 23390 Hydrochloride | PotassiumChannel | Potassium Channel | DopamineReceptor | Dopamine Receptor | Dopamine | D5 | D1 | 5HTReceptor | 5-HT Receptor | 5HT Receptor |
| Inhibitors Related | Minoxidil sulfate | Alverine citrate | Dapoxetine hydrochloride | Tannic acid | Clozapine N-Oxide | Hydrochlorothiazide | Octopamine hydrochloride | D-Menthol | Ursodeoxycholic acid | Oxolinic acid | Trazodone hydrochloride | Indapamide |
| Related Compound Libraries | Pain-Related Compound Library | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Antidepressant Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | GPCR Compound Library | Serotonin Receptor-Targeted Compound Library | Anti-Hypertension Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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