Product Details
Product Name:
SB-633825 |
CAS No.:
956613-01-7 |
Supply Ability:
10g |
Release date:
2025/07/18 |
Product Introduction
Bioactivity
Name | SB-633825 |
Description | SB-633825 can inhibit cancer cell growth and angiogenesis. SB-633825 is an effective and ATP-competitive inhibitor of TIE2, LOK, and BRK (IC50s: 3.5 nM, 66 nM, 150 nM, respectively). |
In vitro | SB-633825 (0.1 μM) inhibits LOK to 44% maximal activity and TIE2 to 75% maximal activity. SB-633825 inhibits TIE2 Tyrosine-protein kinase, lymphocyte-oriented kinase (LOK; STK10), and breast tumor kinase (Brk; PTK6) [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Keywords | TIE2 | SB-633825 | SB633825 | SB 633825 | LOK | BRK |
Inhibitors Related | evobrutinib | (±)-Zanubrutinib | JAK3/BTK-IN-1 | CP-547632 | BMS-986142 | Edralbrutinib | Ibrutinib | IBT6A | Orelabrutinib | Atuzabrutinib | CGI-1746 | Tyrosinase-IN-16 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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